Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
PPEF-1, a RdgC type serine/threonine phosphatase, is homologous to the Drosophila retinal degeneration C gene (rdgc) which is required to prevent light-induced retinal degeneration. However, elimination of PPEF function does not result in retinal degeneration in vertebrates. PPEF/RdgC subfamily members are characterized by C-terminal EF-hands (i. e., two or more EF-hand calcium-binding motifs).
Western Blot analysis of PPEF1 expression in transfected 293T cell line by PPEF1 monoclonal antibody (M01), clone 1F6-1A5.Lane 1: PPEF1 transfected lysate(75.8 KDa).Lane 2: Non-transfected lysate.
Western blot analysis of PPEF1 over-expressed 293 cell line, cotransfected with PPEF1 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with PPEF1 monoclonal antibody (M01), clone 1F6-1A5 . GAPDH ( 36.1 kDa ) used as specificity and loading control.