Mouse PPARD / PPAR Delta

Rabbit

Mouse (tested or 100% immunogen sequence identity)

IgG Polyclonal

Unconjugated

Purified

Unmodified

Synthetic peptide corresponding to amino acids 1-14 of mouse PPAR delta. (N-TERMINAL).

N-Terminus

Detects peroxisome proliferator-activated receptor, delta (PPARD), a member of the nuclear hormone receptor subfamily. Upon activation, PPARD forms heterodimers with retinoid X receptors (RXRs), and functions to regulate transcription of specific gene sequences. PPARD controls genes involved in lipid metabolism, and enhances fatty acid catabolism and energy uncoupling in adipose tissue and skeletal muscle. PPARD has also been implicated in the proliferation and differentiation of preadipocytes, enterocytes, keratinocytes and the placenta. PPARD agonists could be used therapeutically to target multiple components of the metabolic syndrome, including insulin resistance, hyperglycemia, dyslipidemia, and atherosclerosis.

• Western blot (1:500 - 1:2000)
• ELISA (1:2000 - 1:8000)

Western Blot: LS-C42582 detects a band of approximately 55kD in heart whole cell lysates.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: Q03181 NCBI: NM_006238 NP_006229.1