Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
Products
Antibodies
ELISA and Assay Kits
Research Areas
Infectious Disease
Resources
Purchasing
Reference Material
Contact Us
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
PP2Ac / PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
Protein phosphatase 2A alpha (PPP2CA), is a PP2A type serine/threonine phosphatase. PP2A members are composed of a common heterodimeric core enzyme (a catalytic subunit C and a constant regulatory subunit PR65 or A) that associates with a wide variety of regulatory subunits (subunit B). PPP2CA is a catalytic subunit that plays a role in transcription, translation, cell cycle control, and the regulation of most major metabolic pathways. Additionally, it may function as a tumor promoter or suppressor depending on the cell type or the transforming agent.
| Gene Name: | protein phosphatase 2, catalytic subunit, alpha isozyme |
| Family/Subfamily: | Protein Phosphatase , PP2A |
| Synonyms: | PPP2CA, PP2Ac, PP2Calpha, ppp2A1, Protein phosphatase 2A alpha, Replication protein C, PP2CA, RP-C, PP2A-alpha |
| Target Sequences: | NM_002715 NP_002706.1 P67775 |
Publications (2)
1
The tumor suppressor PP2A is functionally inactivated in blast crisis CML through the inhibitory activity of the BCR/ABL-regulated SET protein. Neviani P, Santhanam R, Trotta R, Notari M, Blaser BW, Liu S, Mao H, Chang JS, Galietta A, Uttam A, Roy DC, Valtieri M, Bruner-Klisovic R, Caligiuri MA, Bloomfield CD, Marcucci G, Perrotti D. Cancer cell. 2005 8:355-68. (IP)
[PubMed:16286244]
2
Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells. Singh AP, Bafna S, Chaudhary K, Venkatraman G, Smith L, Eudy JD, Johansson SL, Lin MF, Batra SK. Cancer letters. 2008 259:28-38. (IHC, WB)
[PubMed:17977648]
[PMC:PMC2784916]
☰ Filters
Products
Antibodies
(61)
Proteins
(4)
ELISA Kits
(3)
Type
Cell-Based
(1)
Cell-Based Phosphorylation
(1)
Over-Expression Lysate
(2)
Primary
(61)
Recombinant
(2)
Sandwich
(1)
Target
PP2Ac / PPP2CA
(68)
Reactivity
Human
(58)
Mouse
(51)
Rat
(44)
Bat
(10)
Bovine
(14)
Chicken
(12)
Chimpanzee
(6)
Dog
(12)
Drosophila
(3)
Gibbon
(9)
Guinea pig
(10)
Hamster
(4)
Horse
(9)
Monkey
(10)
Pig
(13)
Rabbit
(20)
Xenopus
(10)
Zebrafish
(10)
Application
IHC
(21)
IHC-P
(11)
WB
(54)
ELISA
(20)
ICC
(3)
IF
(14)
IP
(10)
Peptide-ELISA
(3)
Host
rabbit
(55)
mouse
(4)
rat
(2)
Product Group
IHCPlus
(2)
Isotype
IgG
(32)
IgG1
(1)
IgG2b
(2)
IgG2b,k
(2)
Clonality
monoclonal mc
(6)
polyclonal pc
(55)
Clone
2G9
(1)
P6C7
(1)
Format
96-Well Microplate
(3)
APC Conjugated
(2)
Azide-free
(1)
Biotin Conjugated
(6)
FITC Conjugated
(6)
HRP Conjugated
(6)
Magnetic beads Conjugated
(1)
PE Conjugated
(2)
Sepharose Conjugated
(1)
Unconjugated
(37)
Epitope
aa88-116
(7)
aa296-309
(6)
N-Terminus
(4)
aa188-237
(4)
aa23-72
(4)
aa62-111
(4)
pTyr307
(4)
250-330 aa
(2)
C-Terminus
(1)
Thr301
(1)
aa1-30
(1)
aa1-309
(1)
aa209-309
(1)
aa21-31
(1)
aa260-309
(1)
aa6-20
(1)
p307
(1)
Publications
No
(68)
Sample Type
Adherent Cell Cultures
(2)
Cell Lysates
(1)
Tissue Homogenates
(1)
Tag
GST
(1)
Myc-DDK (Flag)
(3)
Species
Human
(3)
Source
293T Cells
(1)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
Purification
Purified
(1)
Wheat Germ Extract
GST
62 kDa
10 µg/$479; 25 µg/$670
PP2Ac / PPP2CA Mouse anti-Human Monoclonal (P6C7) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µl/$460
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (aa1-309) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (aa296-309) Antibody
Rabbit, Mouse, Rat, Human
IP, WB
Unconjugated
200 µg/$854
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (p307) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PP2Ac / PPP2CA Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$459; 100 µl/$688
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Zebrafish, Pig, Rat, Bovine, Rabbit, Mouse, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$321
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (pTyr307) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (aa260-309) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (pTyr307) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (250-330 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (250-330 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (aa62-111) (Biotin) Antibody
Xenopus, Chicken, Drosophila, Rat, Hamster, Bat, Pig, Horse, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$564
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (Thr301) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$380
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal (N-Terminus) (Magnetic beads) Antibody
Mouse, Rat, Human
IP
Magnetic beads Conjugated
100 µg/$399
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PP2Ac / PPP2CA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PP2Ac / PPP2CA Rat anti-Human Monoclonal (aa209-309) Antibody
Human
IF, IHC, IHC-P
Unconjugated
100 µg/$872
Viewing 1-25
of 68
product results
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
