Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rabbit Polyclonal (IgG) to Human POLH / DNA Polymerase Eta
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Rabbit Polyclonal to Human POLH / DNA Polymerase Eta
Human POLH / DNA Polymerase Eta
Human (tested or 100% immunogen sequence identity)
Specificity and Use
POLH / DNA Polymerase Eta antibody was raised against the epitope recognized by this antibody maps to a region between residue 640 and 690 of human polymerase (DNA directed), eta using the numbering given in entry NP_006493.1 (GeneID 5429).
Species cross-reactivity: Human. Other species not yet tested.
POLH Antibody, Polymerase (DNA directed), eta Antibody, RAD30 Antibody, RAD30A Antibody, DNA polymerase eta Antibody, RAD30 homolog A Antibody, XP-V Antibody, XPV Antibody
DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes.