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POLG

polymerase (DNA directed), gamma

Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.

Gene Name: polymerase (DNA directed), gamma
Synonyms: POLG, DNA polymerase gamma, MIRAS, MTDPS4A, PEO, POLG1, POLGA, SANDO, PolG, catalytic subunit, PolG-alpha, SCAE, DNA polymerase subunit gamma-1, MTDPS4B
Target Sequences: NM_002693 NP_002684.1 P54098

☰ Filters
Antibodies (21)
Proteins (6)
ELISA Kits (1)
Over-Expression Lysate (4)
Primary (21)
Recombinant (2)
Sandwich (1)
POLG (28)
Human (21)
Mouse (6)
Rat (6)
Bat (3)
Bovine (3)
Gibbon (3)
Hamster (3)
Pig (3)
IHC (3)
IHC-P (2)
WB (18)
ELISA (3)
ICC (1)
IF (1)
Peptide-ELISA (1)
rabbit (20)
mouse (1)
Product Group
IHCPlus (2)
IgG (6)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (20)
96-Well Strip Plate (1)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (8)
aa1041-1239 (8)
aa242-291 (4)
aa26-276 (1)
aa462-490 (1)
No (28)
Cell Lysates (1)
Tissue Homogenates (1)
GST, N-terminus (1)
His-S (1)
Myc-DDK (Flag) (4)
Human (4)
293T Cells (2)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
POLG Antibody - Anti-POLG antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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POLG Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
POLG Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)
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POLG Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
POLG Antibody - 1:100 staining mouse kidney tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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POLG Rabbit anti-Human Polyclonal (aa462-490) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
POLG Mouse anti-Human Monoclonal (aa26-276) Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$860
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POLG Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
POLG Antibody - Positive Western Blot detected in 293T whole cell lysate. All lanes: POLG antibody at 4.7 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 140 KDa. Observed band size: 140 KDa
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POLG Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
POLG Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
POLG Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
POLG Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
POLG Antibody - Western blot of POLG antibody.
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POLG Rabbit anti-Human Polyclonal (aa1041-1239) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
POLG Antibody - Western blot of POLG antibody.
Select
POLG Rabbit anti-Human Polyclonal (aa1041-1239) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593
POLG Antibody - Western blot of POLG antibody.
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POLG Rabbit anti-Human Polyclonal (aa1041-1239) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
POLG Antibody - Western blot of POLG antibody.
Select
POLG Rabbit anti-Human Polyclonal (aa1041-1239) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716
POLG Antibody - Western blot of POLG antibody.
Select
POLG Rabbit anti-Human Polyclonal (aa1041-1239) (PE) Antibody
Human
WB
PE Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
POLG Antibody - Western blot of POLG antibody.
Select
POLG Rabbit anti-Human Polyclonal (aa1041-1239) (Cy3) Antibody
Human
WB
Cy3 Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
POLG Antibody - Western blot of POLG antibody.
Select
POLG Rabbit anti-Human Polyclonal (aa1041-1239) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
POLG Antibody - Western blot of POLG antibody.
Select
POLG Rabbit anti-Human Polyclonal (aa1041-1239) (APC, Cy7) Antibody
Human
WB
APC, Cy7 Conjugated
100 µl/$505; 200 µl/$648; 500 µl/$1,152; 1 ml/$1,401; 2 ml/$1,961; 5 ml/$3,676
POLG Antibody - POLG antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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POLG Rabbit anti-Rat Polyclonal (aa242-291) Antibody
Rat
WB
Unconjugated
100 µl/$424
POLG Antibody - POLG antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
POLG Rabbit anti-Rat Polyclonal (aa242-291) (HRP) Antibody
Rat, Hamster, Pig, Bat, Mouse, Bovine, Human, Gibbon
WB
HRP Conjugated
100 µl/$469
POLG Antibody - POLG antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
POLG Rabbit anti-Rat Polyclonal (aa242-291) (Biotin) Antibody
Rat, Hamster, Pig, Bat, Mouse, Bovine, Human, Gibbon
WB
Biotin Conjugated
100 µl/$469
POLG Antibody - POLG antibody Western blot of Rat Lung lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
POLG Rabbit anti-Rat Polyclonal (aa242-291) (FITC) Antibody
Rat, Hamster, Pig, Bat, Mouse, Bovine, Human, Gibbon
WB
FITC Conjugated
100 µl/$469
POLG Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
POLG Protein - Recombinant  Polymerase DNA Directed Gamma 1 By SDS-PAGE
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E. coli
His-S
26.4 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
POLG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
139.4 kDa
100 µg/$710
POLG ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
Viewing 1-25 of 28 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).