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Anti-POLE / POLE1 Antibody (aa1-176) LS-C22848

Ordering

Wt. Vol. Conc. Price
- 500 µl 0.2 mg/ml $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular POLE / POLE1 Antibodies

Anti-POLE / POLE1 Antibody (aa1-176) LS-C22848
Mouse Monoclonal (IgG1,k) to Human POLE / POLE1
Human, Monkey, Mouse, Bovine
Western blot, Immunoprecipitation
Unconjugated
Anti-POLE / POLE1 Antibody (aa1261-1310) LS-C119909
Rabbit Polyclonal (IgG) to Human POLE / POLE1
Human, Rat
IHC - Paraffin, ELISA
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1,k) to Human POLE / POLE1
Human, Monkey, Mouse, Bovine
Western blot, Immunoprecipitation
Unconjugated

Details

Human POLE / POLE1
Mouse
Human, Monkey, Mouse, Bovine (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • Western blot (2 - 4 µg/ml)
  • Immunoprecipitation

Specificity and Use

POLE / POLE1 antibody was raised against purified recombinant protein containing sequence corresponding to residues 1-176 of human Pol e.
aa1-176
Recognizes DNA polymerase e (Pol e) at >200kD. Also recognizes a 140kD form of Pol e, known as Pol e. Species Reactivity: Detects both Pol e and Pol e of Human, Monkey, bovine and Mouse. A mixture of clones 0. N.250 and 0. N.251 will recognize Pol e from D. melanogaster (Pol e only), T. in insect cells (Pol e only), S. cerevisiae (Pol e and Pol e*), X. laevis (Pol e only) and Chicken (Pol e only).
Suitable for use in Immunoprecipitation and Western Blot. Immunoprecipitation (Native and Denatured): 2 ug/mg protein lysate. Western Blot: 2-4 ug/ml for 2hrs at RT.

Packaging

10 mM PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About POLE / POLE1

Q07864 NM_006231 NP_006222.2

POLE Antibody, POLE1 Antibody, DNA polymerase II subunit A Antibody

POLE / POLE1 is the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

Requested From: United States
Date Requested: 12/10/2016

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