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POLB / DNA Polymerase Beta
polymerase (DNA directed), beta
Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.
| Gene Name: | polymerase (DNA directed), beta |
| Synonyms: | POLB, DNA pol beta, Mutant DNA polymerase beta, DNA polymerase beta, DNA polymerase beta subunit |
| Target Sequences: | NM_002690 NP_002681.1 P06746 |
Publications (2)
1
Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. Sobol RW, Foley JF, Nyska A, Davidson MG, Wilson SH. DNA repair. 2003 2:609-22.
[PubMed:12713817]
Related Antibodies: LS-C153861.
2
DNA polymerase beta-dependent long patch base excision repair in living cells. Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH. DNA repair. 2010 9:109-19.
[PubMed:20006562]
[PMC:PMC2819632]
Related Antibodies: LS-C153861.
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POLB / DNA Polymerase Beta
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POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$502
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
E. coli
His
40.3 kDa
100 µg/$361; 500 µg/$739; 20 µg/$261
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (aa286-335) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$287; 50 µl/$341; 100 µl/$431; 200 µl/$539
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
POLB / DNA Polymerase Beta Mouse anti-Human Polyclonal (aa1-335) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µg/$705
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (aa15-188) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (270-350 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (Gln324) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µl/$386
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$391; 100 µl/$489
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, WB
Unconjugated
25 µl/$304
POLB / DNA Polymerase Beta Mouse anti-Rat Monoclonal Antibody
Frog, Hamster, Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$860
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µg/$294; 100 µg/$360
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µl/$680
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (aa107-156) Antibody
Human
WB
Unconjugated
100 µl/$424
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$575
POLB / DNA Polymerase Beta Rabbit anti-Human Polyclonal (aa122-335) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
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of 37
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