Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Immunofluorescence, Western blot, Immunoprecipitation
Mouse Monoclonal [clone AT2G2] (IgG2b) to Human PNPLA2 / ATGL
Western blot, ELISA
Human PNPLA2 / ATGL
Human (tested or 100% immunogen sequence identity)
IgG2b Monoclonal [AT2G2]
Western blot (1:1000 - 1:2000)
IHC - Paraffin
Specificity and Use
PNPLA2 / ATGL antibody was raised against recombinant human ATGL (30-504aa) purified from E. coli. NCBI Accession No.: NP_065109.
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1000-1:2000.
PBS, pH 7.4, 0.1% sodium azide
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
Catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. Also has acylglycerol transacylase activity. May act coordinately with LIPE/HLS within the lipolytic cascade. Regulates adiposome size and may be involved in the degradation of adiposomes. May play an important role in energy homeostasis.