Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
IHC - Paraffin
IHC - Frozen
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
PNMT antibody was raised against phenylethanolamine-N-methyltransferase from bovine adrenal medulla (Sigma).
Recognizes PNMT. Absorption with 10-100 ug immunogen per ml diluted antiserum abolishes the staining. Species cross-reactivity: Rat.
Suitable for use in Immunohistochemistry (frozen and paraffin sections). Immunohistochemistry: 1:400-1:800 (PAP) with overnight incubation at 4?C. Positive control: DEPC-fixed paraffin sections of rat adrenal gland.
Lyophilized from PBS, pH 7.2, 0.1% Sodium Azide, 1% BSA
50 µl Reconstitute in 100 ul of Sterile 40-50% glycerol, distilled water.
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
PNMT catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.