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Anti-PML Antibody LS-C126143

Catalog Size Price
LS-C126143-500 500 µg Unavailable

Related Products

57 PML Antibodies

Most Popular PML Antibodies

Anti-PML Antibody (aa470-499) LS-C98465
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Anti-PML Antibody (aa588-637) IHC-plus™ LS-B3501
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Anti-PML Antibody (aa59-239) LS-C296061
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Anti-PML Antibody IHC-plus™ LS-B13361
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100% Guaranteed
Mouse Monoclonal (IgG1,k) to Human PML
Human
Western blot
Unconjugated

Details

Human PML
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal
Unconjugated
Purified
Unmodified

Applications

Western blot (1:2000)

Specificity and Use

PML antibody was raised against recombinant partial human PML.
Recognizes human normal PML proteins of lower molecular weight, and also recognizes the high molecular weight PML/RARa chimeric protein in promyelocytic leukemia patients.
Suitable for use in Western blot: 1:2000 to differentiate normal PML and chimeric PML/RARa molecules based on their molecular weight.

Packaging

Lyophilized from 0.01 M PBS, pH 7.4
Sterile 40-50% glycerol, distilled water.
Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstituted product is stable for 12 months at -20°C Aliquot and store at -20°C.
For research use only.

About PML

P29590 NM_002675 NP_002666.1

PML Antibody, PP8675 Antibody, Promyelocytic leukemia Antibody, Protein PML Antibody, TRIM19 Antibody, Promyelocytic leukemia protein Antibody, RING finger protein 71 Antibody, MYL Antibody, RNF71 Antibody

Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions.

Requested From: 
Date Requested: 12/12/2017

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