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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PMEL / SILV / gp100 Antibody (Azide‑free) LS‑C25588
Antibody
Gp100 antibody LS-C25588 is an unconjugated mouse monoclonal antibody to human gp100 (PMEL / SILV). Validated for IHC.
Catalog
Size
Price
LS-C25588-100
100 µl
Unavailable
LS-C25588-1000
1000 µl
Unavailable

Popular PMEL / SILV / gp100 Products

Antibody
Species: Human
Applications: IHC, IHC - Frozen
Antibody
Species: Human
Applications: Western blot, ELISA
Anti-PMEL / SILV antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2662 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin
Antibody
Species: Human
Applications: Western blot, ELISA
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SILV (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SILV.
Species: Human
Applications: Western blot

Product Description

Gp100 antibody LS-C25588 is an unconjugated mouse monoclonal antibody to human gp100 (PMEL / SILV). Validated for IHC.
About PMEL / SILV / gp100
PMEL / SILV / gp100 is a melanocyte-specific type I transmembrane glycoprotein. The encoded protein is enriched in melanosomes, which are the melanin-producing organelles in melanocytes, and plays an essential role in the structural organization of premelanosomes. This protein is involved in generating internal matrix fibers that define the transition from Stage I to Stage II melanosomes. P40967 NM_006928 NP_008859.1

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Specifications

Target
Human PMEL / SILV / gp100
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free
Applications
  • IHC
  • IHC - Frozen
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Melanoma Associated Antigen (100/7).
Specificity
Recognizes a (pre) melanosomal 100+7kD antigen (glycoprotein). Reacts with melanomas, clear cell sarcomas (melanoma of soft tissue), nevocellular nevi and normal melanocytes. Except for one case of non-Hodgkin's lymphoma in which macrophages were positive, no reactions with other tumors or tissues have been observed.
Usage
Suitable for use in Immunohistochemistry (Immunoperoxidase staining on frozen tissue sections). Immunohistochemistry: 1:5-1:20 with PBS. Formalin fixation and embedding in paraffin may affect the reactivity of the antibody. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Presentation
PBS, pH 7.4. No stabilizing proteins added. No preservative added.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/20/2018

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