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Anti-PMAIP1 / NOXA Antibody (clone 114C307.1) LS-C571

Note: This antibody replaces LS-C73718

Ordering

Wt. Vol. Conc. Price
100 µg 200 µl 0.5 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Mouse Monoclonal [clone 114C307.1] (IgG1) to Human PMAIP1 / NOXA
Human
Western blot
Unconjugated

Details

Human PMAIP1 / NOXA
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [114C307.1]
Protein G purified

Applications

Western blot (1 - 2 µg/ml)

Specificity and Use

PMAIP1 / NOXA antibody was raised against recombinant human PMAIP1 / NOXA.
An ~80 kD background band may also be seen in Jurkat cell lysate.

Packaging

PBS, 0.2% gelatin, 0.05% sodium azide.
Long term: -70°C; Short term: +4°C
For research use only.

About PMAIP1 / NOXA

Q13794 NM_021127 NP_066950.1

PMAIP1 Antibody, NOXA Antibody, PMA-induced protein 1 Antibody, Protein Noxa Antibody, APR Antibody

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 By similarity. Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Western blot

Western blot
Western blot detection of Noxa in RL-7 cell (a follicular lymphoma) lysate. A protein of approximate molecular weight of 11 kD is detected using antibody at 2 ug/ml.
 

Requested From: United States
Date Requested: 9/30/2016

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