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Anti-PLN / Phospholamban Antibody (N-Terminus, Sepharose) LS-C171976

Catalog	Size	Price
LS-C171976-100	100 µg	Unavailable

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Anti-PLN / Phospholamban Antibody (phospho-Thr17, Biotin) LS-C266487

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Antibody:	Rabbit Polyclonal to Human PLN / Phospholamban
Reactivity:	Human, Mouse, Rat
Application:	Immunoprecipitation (applications tested for the base form of this product only)
Format:	Sepharose Conjugated

Details

Target:	Human PLN / Phospholamban
Host:	Rabbit
Reactivity:	Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality:	Polyclonal
Conjugations:	Sepharose. Also available Unconjugated or conjugated with Magnetic beads.
Purification:	Immunoaffinity purified
Modifications:	Unmodified

Applications

Approved:

Immunoprecipitation
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:	PLN / Phospholamban antibody was raised against synthetic peptide corresponding to a sequence at the N-terminal of human Phospholamban, identical to the related rat and mouse sequence.
Epitope:	N-Terminus
Specificity:	Rat, mouse. No cross reactivity with other proteins.

Packaging

Presentation:	50% slurry in PBS, pH 7.2, 0.01 mg sodium azide
Storage:	Store at 4°C
Restrictions:	For research use only.

About PLN / Phospholamban

Uniprot: P26678 NCBI: NM_002667 NP_002658.1

Synonyms: PLN Antibody, CMD1P Antibody, CMH18 Antibody, PLB Antibody, Cardiac phospholamban Antibody, Phospholamban Antibody

Description: Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca2+. Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN.

(More About PLN / Phospholamban)

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Western blot

This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From:
Date Requested: 6/24/2017

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