Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(applications tested for the base form of this product only)
Specificity and Use
PLIN3 / M6PRBP1 / TIP47 antibody was raised against a synthetic peptide made to a region within the C-terminus (within residues 350-435) of the human TIP47 protein. [Swiss-Prot# O60664] Percent identity by BLAST analysis: Mouse (84%).
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PLIN3 Antibody, 47 kDa MPR-binding protein Antibody, Cargo selection protein TIP47 Antibody, Perilipin 3 Antibody, Placental protein 17 Antibody, PP17 Antibody, M6PRBP1 Antibody, TIP47 Antibody, Perilipin-3 Antibody
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo.
Anti-PLIN3 / M6PRBP1 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B253 concentration 5 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of TIP47 in 3T3 L1 lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Detection of TIP47/M6PRBP1 in 3T3 L1 lysates. This image was taken for the unconjugated form of this product. Other forms have not been tested.