Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 2F7] (IgG1,k) to Human PLIN3 / M6PRBP1 / TIP47
IHC - Paraffin, Western blot, ELISA
Guinea pig Polyclonal (IgG) to Human PLIN3 / M6PRBP1 / TIP47
IHC - Frozen, Western blot
Human PLIN3 / M6PRBP1 / TIP47
Human, Bovine (tested or 100% immunogen sequence identity)
IHC - Frozen
Western blot (1:1000)
Specificity and Use
Synthetic peptide of TIP47 N-terminus (aa1-16).
Recognizes human TIP47/PP17. Does not cross-react with adipophilin and perilipin. Reactivity on Cultured Cell Lines 3T3 cells. Species cross-reactivity: Bovine.
Suitable for use in Western Blot and Immunohistochemistry (frozen tissue; paraffin sections after microwave treatment). Immunohistochemistry: 1:100-1:200; Incubation Time 1hr at RT. Western Blot: 1:1000. Using ECL.
0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
PLIN3 Antibody, 47 kDa MPR-binding protein Antibody, Cargo selection protein TIP47 Antibody, Perilipin 3 Antibody, Placental protein 17 Antibody, PP17 Antibody, M6PRBP1 Antibody, TIP47 Antibody, Perilipin-3 Antibody
Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo.