Human PLG / Plasmin / Plasminogen

Mouse

Human (tested or 100% immunogen sequence identity)

IgG2b Monoclonal

4D2

Unconjugated

Ion exchange chromatography

Unmodified

Purified human plasminogen.

Recognizes human plasminogen, a single chain beta globulin of 80-90kD. It is a circulating zymogen that is converted to the active enzyme plasmin (fibrinolysin) by plasminogen activators. The main function of plasmin is to dissolve fibrin and thus break up blood clots. Plasmin also plays a proteolytic role in processes such as embryonic development, tissue remodeling, tumor invasion and inflammation. Plasminogen deficiency may be a cause of thrombosis, or may be acquired through acute liver disease, acute disseminated intravascular coagulation or through thrombolytic therapy with plasminogen activators. Does not cross-react with other human serum proteins.

• IHC - Paraffin
• ELISA

Immunohistology: This product does not require protein digestion pre-treatment of paraffin embedded sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin embedded sections.

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P00747 NCBI: NM_000301 NP_000292.1