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PLCG2 / PLC Gamma 2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCG2 / PLC Gamma 2 is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3.
| Gene Name: | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| Family/Subfamily: | Phospholipase , not assigned-Phospholipase |
| Synonyms: | PLCG2, FCAS3, Phospholipase C-gamma-2, PLCG 2, PLC-IV, APLAID, Phospholipase C-IV, PLC-gamma-2 |
| Target Sequences: | NM_002661 NP_002652.2 P16885 |
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PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr1217) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
HEK 293 Cells
Myc-DDK (Flag)
147.7 kDa
20 µg/$1,107
Cell-Based Phosphorylation
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$668
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr753) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr1217) Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Horse, Human, Monkey
IHC
Unconjugated
100 µg/$570
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (aa721-770) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr759) Antibody
Mouse, Rat, Human, Monkey
WB
Unconjugated
100 µl/$315
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr753) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (1160-1240 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (pTyr1217) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
E. coli
His-T7
29.3 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Cell-Based
96-Well Microplate
Mouse, Human, Rat
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (aa1186-1235) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PLCG2 / PLC Gamma 2 Mouse anti-Human Monoclonal (1E10C11) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$459
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (1160-1240 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (690-770 aa) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal Antibody
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Horse, Human, Monkey
IF, IHC
Unconjugated
50 µg/$489
PLCG2 / PLC Gamma 2 Rabbit anti-Human Polyclonal (p1217) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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