PLCG1

phospholipase C, gamma 1

PLCG1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

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Products

Antibodies (72)

ELISA Kits (16)

Proteins (7)

Type

Cell-Based (1)

Cell-Based Phosphorylation (3)

Custom (2)

Over-Expression Lysate (4)

Primary (72)

Recombinant (3)

Sandwich (9)

Sandwich CLIA (1)

Target

PLCG1 (95)

Reactivity

Human (81)

Mouse (69)

Rat (57)

Bovine (13)

Dog (4)

Horse (4)

Monkey (15)

Rabbit (7)

Xenopus (4)

Zebrafish (2)

Application

IHC (31)

IHC-P (11)

WB (68)

Flo (5)

ELISA (23)

ICC (5)

IF (13)

IP (12)

Peptide-ELISA (11)

Host

rabbit (57)

mouse (15)

Product Group

IHCPlus (3)

Isotype

IgG (34)

IgG1 (8)

IgG1,k (1)

IgG2a (2)

IgG2a,k (3)

Clonality

monoclonal mc (15)

polyclonal pc (57)

Clone

2A2 (1)

2B1 (1)

2F3D11 (1)

2F3E10 (1)

3C2D11 (1)

3H1C10 (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (5)

96-Well Strip Plate (9)

APC (1)

APC Conjugated (2)

Biotin Conjugated (2)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (2)

Unconjugated (60)

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Epitope

pTyr783 (9)

aa1091-1290 (8)

pTyr771 (5)

pTyr1253 (4)

710-790 aa (2)

C-Terminus (2)

Internal (2)

1190-1270 aa (1)

720-800 aa (1)

Ab-1253 (1)

Gly765 (1)

Gly777 (1)

Tyr783 (1)

aa1221-1270 (1)

aa1240-1290 (1)

aa456-488 (1)

aa736-785 (1)

aa751-800 (1)

aa758-790 (1)

p771 (1)

p783 (1)

pSer1248 (1)

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Publications

No (95)

Sample Type

Adherent Cell Cultures (4)

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (8)

Serum (8)

Tissue Homogenates (3)

Urine (1)

Tag

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (1)

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IHC-plus™ PLCG1 Antibody (clone 2B1) LS-B7825

(4.0) Rating

Antibody:

PLCG1 Mouse anti-Human Monoclonal (2B1) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$460

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PLCG1 Antibody (phospho-Tyr783) LS-C199475

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (pTyr783) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

PLCG1 Antibody (clone 3H1C10) LS-C669421

Antibody:

PLCG1 Mouse anti-Human Monoclonal (3H1C10) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

IHC-plus™ PLCG1 Antibody (C-Terminus) LS-B2311

(4.0) Rating

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$565

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Mouse/Human/Rat Phospho-PLCG1 (Tyr1253) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1209

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Mouse/Human/Rat Phospho-PLCG1 (Tyr783) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1094

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

Select

Mouse/Human/Rat PLCG1 (Cell-Based ELISA) ELISA Kit - LS-F2258

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

Select

PLCG1 Antibody (phospho-Tyr783) LS-C354053

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (pTyr783) Antibody

Reactivity:

Mouse, Bovine, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$315

Select

PLCG1 Antibody (clone 3C2D11) LS-C669327

Antibody:

PLCG1 Mouse anti-Human Monoclonal (3C2D11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

PLCG1 Antibody (phospho-Tyr771) LS-C801045

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (pTyr771) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

IHC-plus™ PLCG1 Antibody (aa751-800) LS-B6987

(4.0) Rating

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (aa751-800) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

PLCG1 Antibody LS-C131417

Antibody:

PLCG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$489

Select

PLCG1 Antibody LS-C801570

Antibody:

PLCG1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PLCG1 Antibody (phospho-Tyr783) LS-C801046

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (pTyr783) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PLCG1 Antibody (phospho-Tyr783) LS-C9600

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (pTyr783) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$717

Select

PLCG1 Antibody (clone 2F3D11) LS-C682409

Antibody:

PLCG1 Mouse anti-Human Monoclonal (2F3D11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

PLCG1 Antibody (clone 2A2) LS-C197919

Antibody:

PLCG1 Mouse anti-Human Monoclonal (2A2) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

PLCG1 Antibody LS-C9591

Antibody:

PLCG1 Mouse anti-Bovine Monoclonal Antibody

Reactivity:

Rabbit, Mouse, Bovine, Rat, Human

Applications:

ELISA, ICC, IP, WB

Format:

Unconjugated

Price:

50 µg/$725

Select

PLCG1 Antibody (aa736-785) LS-C117571

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (aa736-785) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

PLCG1 Antibody (phospho-Tyr771) LS-C199474

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (pTyr771) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

PLCG1 Antibody (C-Terminus) LS-C352671

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

PLCG1 Antibody (phospho-Tyr1253) LS-C352668

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (pTyr1253) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$315

Select

PLCG1 Antibody (710-790 aa) LS-C385570

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (710-790 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

PLCG1 Antibody (720-800 aa) LS-C380827

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (720-800 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

PLCG1 Antibody (710-790 aa) LS-C381203

Antibody:

PLCG1 Rabbit anti-Human Polyclonal (710-790 aa) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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