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Anti-PLCG1 Antibody LS-C9591

Catalog Size Price
LS-C9591-50 50 µg (1.25 mg/ml) Unavailable

Related Products

94 PLCG1 Antibodies

Most Popular PLCG1 Antibodies

Anti-PLCG1 Antibody (C-Terminus) IHC-plus™ LS-B2311
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Anti-PLCG1 antibody IHC of human colon, lymphocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2311 dilution 1:25.
Anti-PLCG1 Antibody (clone 2B1) IHC-plus™ LS-B7825
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Anti-PLCG1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7825 dilution 1:200.
Anti-PLCG1 Antibody (aa1091-1290, Biotin) LS-C684267
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Anti-PLCG1 Antibody (aa1091-1290, FITC) LS-C690476
Rabbit Polyclonal (IgG) to Human PLCG1
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Anti-PLCG1 Antibody (aa1091-1290, Cy3) LS-C697956
Rabbit Polyclonal (IgG) to Human PLCG1
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IHC, Western blot
Cy3 Conjugated

100% Guaranteed
Mouse Monoclonal (IgG) to Bovine PLCG1
Bovine, Human, Mouse, Rat, Rabbit
ICC, Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Bovine PLCG1
Mouse
Bovine, Human, Mouse, Rat, Rabbit (tested or 100% immunogen sequence identity)
IgG Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • ICC (5 - 10 µg/ml)
  • Western blot (0.5 - 2 µg/ml)
  • Immunoprecipitation
  • ELISA

Specificity and Use

PLCG1 antibody was raised against purified soluble phospholipase C (PLC) g-1 from bovine brain.
Recognizes bovine PLC g-1 at 135kD. Reacts with some non-PLC g-1 SH-3 containing proteins, including nck (47kD). Species cross-reactivity: rabbit, rat, mouse and human.
Suitable for use in ELISA, Immunoprecipitation, Western Blot and Immunocytochemistry. Western Blot: 0.5-2 ug/ml detects PLCg1 in human A431 carcinoma cells as well as rabbit and bovine brain cytosol preparations. Immunoprecipitation: 4 ug Immunoprecipitates PLCg1 from non-stimulated A431 cell lysates and from rabbit brain cytosol preparation. Immunocytochemistry: 5-10 ug/ml detects PLCg1 on ethanol-acetic acid (95:5) fixed A431 cells.

Packaging

0.1 M Tris-glycine, pH 7.4, 150 mM sodium chloride, 0.05% sodium azide.
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
For research use only.

About PLCG1

P19174 NM_002660 NP_002651.2

PLCG1 Antibody, Phospholipase C, gamma 1 Antibody, Phospholipase C-148 Antibody, Phosphoinositidase C Antibody, Phospholipase C-II Antibody, Inositoltrisphosphohydrolase Antibody, PLC-gamma-1 Antibody, PLC1 Antibody, PLC-148 Antibody, PLC-II Antibody, PLC148 Antibody, NCKAP3 Antibody, Phospholipase C-gamma-1 Antibody, PLCgamma1 Antibody

PLCG1 catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras.

Requested From: 
Date Requested: 5/20/2018

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