PLA2R / PLA2R1

phospholipase A2 receptor 1, 180kDa

Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells. In neutrophils, binding of sPLA2-IB/PLA2G1B can activate p38 MAPK to stimulate elastase release and cell adhesion. May be involved in responses in proinflammatory cytokine productions during endotoxic shock. Also has endocytic properties and rapidly internalizes sPLA2 ligands, which is particularly important for the clearance of extracellular sPLA2s to protect their potent enzymatic activities. The soluble secretory phospholipase A2 receptor form is circulating and acts as a negative regulator of sPLA2 functions by blocking the biological functions of sPLA2-IB/PLA2G1B.

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Products

Antibodies (27)

ELISA Kits (12)

Proteins (9)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (27)

Recombinant (7)

Sandwich (9)

Sandwich CLIA (1)

Target

PLA2R / PLA2R1 (48)

Reactivity

Human (24)

Mouse (11)

Rat (2)

Chicken (1)

Monkey (2)

Porcine (1)

Rabbit (1)

Sheep (1)

Application

IHC (2)

WB (22)

Flo (1)

ELISA (6)

Peptide-ELISA (1)

Host

rabbit (26)

goat (1)

Isotype

IgG (7)

Clonality

polyclonal pc (27)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (10)

APC (2)

APC Conjugated (2)

Biotin Conjugated (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (10)

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Epitope

aa1418-1487 (8)

aa385-643 (8)

aa395-530 (4)

C-Terminus (2)

aa946-957 (1)

Publications

No (47)

Yes (1)

Sample Type

Plasma (5)

Serum (5)

Tissue Homogenates (2)

Tag

6His, N-terminus (1)

DDK,C-terminus (1)

His (2)

His-GST-S (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (8)

Mouse (1)

Source

293T Cells (1)

CHO Cells (1)

E. coli (3)

HEK 293 Cells (2)

Mammalian Cells (1)

Yeast (1)

Purification

Purified (1)

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PLA2R / PLA2R1 Antibody (C-Terminus) LS-C153547

(4.0) Rating

(1) Publication(s)

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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PLA2R / PLA2R1 Antibody (aa946-957) LS-C108906

Antibody:

PLA2R / PLA2R1 Goat anti-Human Polyclonal (aa946-957) Antibody

Reactivity:

Human, Monkey

Applications:

Flo, Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

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Human PLA2R / PLA2R1 (Sandwich ELISA) ELISA Kit - LS-F21043

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Human PLA2R / PLA2R1 Protein (Recombinant DDK,C-terminus) (aa38-651) - LS-G145315

Source:

CHO Cells

Tag:

DDK,C-terminus

Molecular Weight:

77.5 kDa

Price:

50 µg/$677

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Human PLA2R / PLA2R1 (Sandwich ELISA) ELISA Kit - LS-F7337

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$834

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PLA2R / PLA2R1 Antibody (aa1418-1487) LS-C374775

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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PLA2R / PLA2R1 Antibody (aa1418-1487, HRP) LS-C712800

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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PLA2R / PLA2R1 Antibody (aa1418-1487, Biotin) LS-C688138

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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PLA2R / PLA2R1 Antibody (aa1418-1487, FITC) LS-C695050

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

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PLA2R / PLA2R1 Antibody (aa1418-1487, Cy3) LS-C703776

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3

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Human PLA2R / PLA2R1 Protein (Recombinant His-T7) (aa385-643) - LS-G15374

Source:

E. coli

Tag:

His-T7

Molecular Weight:

33.6 kDa

Price:

10 µg/$292; 50 µg/$512; 100 µg/$817; 200 µg/$1,018; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359

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PLA2R / PLA2R1 Antibody LS-C668183

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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Human PLA2R / PLA2R1 Protein (Recombinant His) (aa395-530) - LS-G23394

Source:

Yeast

Tag:

His

Molecular Weight:

17.45 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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PLA2R / PLA2R1 Antibody LS-C676271

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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Human PLA2R / PLA2R1 (CLIA) ELISA Kit - LS-F29713

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Human PLA2R / PLA2R1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121979

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

152.81 kDa

Price:

100 µg/$710

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PLA2R / PLA2R1 Antibody LS-C496781

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PLA2R / PLA2R1 Antibody LS-C832802

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PLA2R / PLA2R1 Antibody (C-Terminus) LS-C144967

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

200 µl/$468

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PLA2R / PLA2R1 Antibody (aa395-530) LS-C371409

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PLA2R / PLA2R1 Antibody (aa395-530, Biotin) LS-C371416

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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PLA2R / PLA2R1 Antibody (aa395-530, FITC) LS-C371408

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• Biotin
• FITC

• Unconjugated
• Biotin
• FITC

Select

PLA2R / PLA2R1 Antibody (aa385-643) LS-C295908

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

Select

PLA2R / PLA2R1 Antibody (aa385-643, FITC) LS-C302476

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

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PLA2R / PLA2R1 Antibody (aa385-643, PE) LS-C726856

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008

• Unconjugated
• FITC
• PE

• Unconjugated
• FITC
• PE

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