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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PKP2 / Plakophilin 2 Antibody (aa632‑681) LS‑C120222
Plakophilin 2 antibody LS-C120222 is an unconjugated rabbit polyclonal antibody to Plakophilin 2 (PKP2) from human and rat. Validated for Peptide-ELISA and WB.
Catalog
Size
Price
LS-C120222-50
50 µl
Unavailable
LS-C120222-100
100 µl
Unavailable

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Product Description

Plakophilin 2 antibody LS-C120222 is an unconjugated rabbit polyclonal antibody to Plakophilin 2 (PKP2) from human and rat. Validated for Peptide-ELISA and WB.
About PKP2 / Plakophilin 2
PKP2 / Plakophilin 2 is a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. Q99959 NM_004572 NP_004563.2

PKP2 Antibody, ARVD9 Antibody, Plakophilin 2 Antibody, Plakophilin-2 Antibody


Specifications

Target
Human PKP2 / Plakophilin 2
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1:500 - 1:1000)
  • Peptide Enzyme-Linked Immunosorbent Assay (1:20000)
Immunogen
Synthetic peptide from human PKP2 (aa632-681).
Epitope
aa632-681
Specificity
PKP2 Antibody detects endogenous levels of total PKP2 protein.
Presentation
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Storage
Store at -20°C for up to 1 year.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide.

Western blot

Western blot of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide.
Western blot of extracts from HeLa/HepG2 cells, using PKP2 Antibody. The lane on the right is treated with the synthesized peptide.


Requested From: 
Date Requested: 6/23/2018

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