The Immunohistochemistry Antibody Company
|Human, Monkey, Mouse, Rat, Dog (tested or 100% immunogen sequence identity)|
|Bovine, Hamster (at least 90% immunogen sequence identity)|
|PKN1 antibody was raised against a synthetic peptide corresponding to amino acids 911-929 of human PKN (EAPTLSPPRDARPLTAAEQ) was used as immunogen; GenBank no. gi|914098|gb|AAB33345.1|. The peptide immunogen sequence is 100% conserved in rat, mouse and dog. Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Mouse, Rat, Dog (100%); Bovine, Hamster, Elephant, Panda (95%); Bat, Pig (89%).|
|Antiserum, 0.05% sodium azide|
|Store at -20°C. Aliquot to avoid freeze/thaw cycles.|
|For research use only.|
PKN1 Antibody, PKN Antibody, Protein kinase C-like PKN Antibody, Protein kinase N1 Antibody, PRK1 Antibody, PRKCL1 Antibody, Serine-threonine kinase N Antibody, Pknalpha Antibody, Protease-activated kinase 1 Antibody, Protein kinase PKN-alpha Antibody, DBK Antibody, PAK-1 Antibody, PKN-ALPHA Antibody, Protein kinase C-like 1 AntibodyPKC-related serine/threonine-protein kinase involved in various processes such as regulation of the intermediate filaments of the actin cytoskeleton, cell migration, tumor cell invasion and transcription regulation. Regulates the cytoskeletal network by phosphorylating proteins such as VIM and neurofilament proteins NEFH, NEFL and NEFM, leading to inhibit their polymerization.