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Anti-PKLR Antibody (aa521-551) LS-C98971

Ordering

Wt. Vol. Conc. Price
- 400 µl - $305
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PKLR Antibodies

Anti-PKLR Antibody (C-Terminus, Biotin) LS-C281756
Rabbit Polyclonal (IgG) to Human PKLR
Human, Mouse
IHC, Western blot, ELISA
Biotin Conjugated
Anti-PKLR Antibody (C-Terminus, FITC) LS-C281757
Rabbit Polyclonal (IgG) to Human PKLR
Human, Mouse
IHC, Western blot, ELISA
FITC Conjugated
Anti-PKLR Antibody (aa114-323, FITC) LS-C304942
Rabbit Polyclonal (IgG) to Mouse PKLR
Mouse
Western blot, ELISA
FITC Conjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human PKLR
Human, Mouse
IHC - Paraffin, Western blot
Unconjugated

Details

Human PKLR
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (1:50 - 1:100)
  • Western blot (1:1000)

Specificity and Use

PKLR antibody was raised against kLH-conjugated synthetic peptide between amino acids 521-551 from C-terminal region of human PKLR.
LS-E8636 - Lyophilized - 100 µg - $145.00
aa521-551

Packaging

PBS, 0.09% sodium azide
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
For research use only.

About PKLR

P30613 NM_000298 NP_000289.1

PKLR Antibody, PKL Antibody, Pyruvate kinase, liver and RBC Antibody, Pyruvate kinase type L Antibody, Red cell/liver pyruvate kinase Antibody, RPK Antibody, PK1 Antibody, PKR Antibody, Pyruvate kinase 1 Antibody, Pyruvate kinase isozymes R/L Antibody, R-type/L-type pyruvate kinase Antibody, PKRL Antibody, Pyruvate kinase isozyme R/L Antibody

PKLR is a pyruvate kinase that catalyzes the transphosphorylation of phohsphoenolpyruvate into pyruvate and ATP, which is the rate-limiting step of glycolysis. Defects in this enzyme, due to gene mutations or genetic variations, are the common cause of chronic hereditary nonspherocytic hemolytic anemia (CNSHA or HNSHA). Multiple transcript variants encoding different isoforms have been found for this gene.

Immunohistochemistry

Immunohistochemistry
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Western blot

Western blot
PKLR Antibody (G536) western blot of HL-60 cell line lysates (35 ug/lane). The PKLR antibody detected the PKLR protein (arrow).

Western blot

Western blot
The anti-PKLR antibody is used in Western blot to detect PKLR in mouse liver tissue lysate.
 

Requested From: United States
Date Requested: 12/3/2016

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