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PIWIL1 / PIWI

piwi-like RNA-mediated gene silencing 1

Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Probable component of some RISC complex, which mediates RNA cleavage and translational silencing. Also plays a role in the formation of chromatoid bodies and is required for some miRNAs stability (By similarity). Isoform 3 may be a negative developmental regulator.

Gene Name: piwi-like RNA-mediated gene silencing 1
Synonyms: PIWIL1, HIWI, PIWI, Piwi-like 1 (Drosophila), Piwi-like protein 1, Piwi (Drosophila)-like 1, MIWI, Piwi homolog
Target Sequences: NM_004764 NP_004755.2 Q96J94

☰ Filters
Antibodies (26)
Proteins (3)
Over-Expression Lysate (2)
Primary (26)
Recombinant (1)
PIWIL1 / PIWI (29)
Human (26)
Mouse (19)
Rat (16)
Bovine (7)
Chimpanzee (3)
Dog (7)
Gibbon (6)
Guinea pig (6)
Hamster (1)
Horse (7)
Monkey (7)
Pig (7)
Rabbit (7)
Xenopus (1)
IHC (9)
IHC-P (3)
WB (20)
ELISA (6)
ICC (2)
IF (7)
IP (4)
Peptide-ELISA (3)
rabbit (24)
mouse (1)
goat (1)
IgG (13)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (25)
12K163 (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (20)
C-Terminus (4)
aa71-120 (4)
Internal (1)
aa562-574 (1)
aa82-290 (1)
No (29)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
PIWIL1 / PIWI Antibody
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
PIWIL1 / PIWI Antibody - Immunofluorescent analysis of HIWI1 staining in U2OS cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 deg C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IP, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
PIWIL1 / PIWI Antibody
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$332
PIWIL1 / PIWI Antibody - Immunohistochemistry of PIWI-L1 in rat liver tissue with PIWI-L1 antibody at 10 µg/mL.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$341
PIWIL1 / PIWI Antibody - Immunofluorescence analysis of U2OS cells.
Select
PIWIL1 / PIWI Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PIWIL1 / PIWI Antibody - Western blot analysis of HeLa whole cells lysates using MIWI antibody. The lane on the left is treated with the antigen-specific peptide.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IP, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PIWIL1 / PIWI Antibody - Immunohistochemistry of paraffin-embedded human testis tissue at dilution 1:100
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
PIWIL1 / PIWI Antibody - Western blot analysis of extracts of various cell lines, using PIWIL1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 3s.
Select
PIWIL1 / PIWI Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
40 µg/$485
Select
PIWIL1 / PIWI Rabbit anti-Mouse Polyclonal Antibody
Mouse, Human
IF
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
PIWIL1 / PIWI Mouse anti-Human Monoclonal (aa82-290) (12K163) Antibody
Human
ICC
Unconjugated
100 µg/$856
PIWIL1 / PIWI Antibody - Western blot analysis of extracts of mouse testis tissue using PIWL1 antibody. The lane on the left was treated with blocking peptide.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PIWIL1 / PIWI Antibody - Immunofluorescence analysis of U2OS cells using PIWIL1 Polyclonal Antibody at dilution of 1:100.Blue: DAPI for nuclear staining.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PIWIL1 / PIWI Antibody - Goat Anti-PIWI / HIWI Antibody (4µg/ml) staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining.
Select
PIWIL1 / PIWI Goat anti-Human Polyclonal (aa562-574) Antibody
Xenopus, Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC-P, Peptide-ELISA
Unconjugated
100 µg/$503
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PIWIL1 / PIWI Antibody - PIWIL1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal (aa71-120) Antibody
Human
WB
Unconjugated
100 µl/$424
PIWIL1 / PIWI Antibody - PIWIL1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal (aa71-120) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
PIWIL1 / PIWI Antibody - PIWIL1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal (aa71-120) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
PIWIL1 / PIWI Antibody - PIWIL1 antibody Western blot of Fetal Stomach lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal (aa71-120) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
PIWIL1 / PIWI Antibody - PIWIL1 antibody Western blot of CCRF-CEM lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
PIWIL1 / PIWI Antibody - PIWIL1 antibody Western blot of CCRF-CEM lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
PIWIL1 / PIWI Antibody - PIWIL1 antibody Western blot of CCRF-CEM lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PIWIL1 / PIWI Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 29 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).