The Immunohistochemistry Antibody Company
|Human, Mouse (tested or 100% immunogen sequence identity)|
|PINK1 antibody was raised against an N-terminal region synthetic peptide made to the human Pink1 protein sequence (between residues 1-50)|
|The applications listed have been tested for the base form of this product. Alternate forms, such as conjugated, azide-free, or ready-to-use, have not been tested.|
|50 mM sodium borate|
|Store at 4°C. Do not freeze.|
|For research use only.|
PINK1 Antibody, BRPK Antibody, PTEN induced putative kinase 1 Antibody, PARK6 Antibody, PTEN-induced putative kinase Antibody, Protein kinase BRPK AntibodyProtects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2.