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Catalog Number	Size	Price
LS-C501739-50	50 µg	$294
LS-C501739-100	100 µg	$360

Polyclonal Rabbit anti‑Human PINK1 Antibody (HRP) LS‑C501739

Name: Anti-PINK1 Antibody | Rabbit anti-Human Polyclonal HRP ELISA | LSBio
Brand: Lifespan BioSciences
SKU: LS-C501739-50
Price: 294.0000 USD
Availability: InStock

Submit Review LSBio Guarantee

Antibody:

PINK1 Rabbit anti-Human Polyclonal (HRP) Antibody

Application:

ELISA

Reactivity:

Human

Format:

Horseradish Peroxidase, Unmodified

Other formats:

Biotin FITC Unconjugated

$294

LS-C501739-50

Toll Free North America

206-374-1102

For Research Use Only

Specifications Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

PINK1 Rabbit anti-Human Polyclonal (HRP) Antibody

Application:

ELISA

Reactivity:

Human

Format:

Horseradish Peroxidase, Unmodified

Other formats:

Biotin FITC Unconjugated

Specifications

Description

PINK1 antibody LS-C501739 is an HRP-conjugated rabbit polyclonal antibody to human PINK1. Validated for ELISA.

Target

Human PINK1

Synonyms

See All PINK1 Antibodies

Host

Rabbit

Reactivity

Human (tested or 100% immunogen sequence identity)

Clonality

IgG Polyclonal

Conjugations

Horseradish Peroxidase. Also available Unconjugated or conjugated with Biotin, FITC.

Purification

Protein G purified

Modifications

Unmodified

Immunogen

Recombinant human Serine/threonine-protein kinase PINK1, mitochondrial protein (162-272AA)

Specificity

Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Activates PARK2 in 2 steps: (1) by mediating phosphorylation at 'Ser-65' of PARK2 and (2) mediating phosphorylation of ubiquitin, converting PARK2 to its fully-active form (PubMed:24660806, PubMed:24751536, PubMed:24784582, PubMed:25527291).

Applications