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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PINK1 Antibody (aa484‑504) IHC‑plus™ LS‑B1502 Best Seller
Note: This antibody replaces LS-C11705
PINK1 antibody LS-B1502 is an unconjugated rabbit polyclonal antibody to PINK1 from human and monkey. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B1502-1
1 ea
Unavailable

Popular PINK1 Products

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Product Description

PINK1 antibody LS-B1502 is an unconjugated rabbit polyclonal antibody to PINK1 from human and monkey. Validated for IHC and WB. Tested on 20 paraffin-embedded human tissues.
About PINK1
Protects against mitochondrial dysfunction during cellular stress by phosphorylating mitochondrial proteins. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) by mediating activation and translocation of PARK2. Targets PARK2 to dysfunctional depolarized mitochondria through the phosphorylation of MFN2. Q9BXM7 NM_032409 NP_115785.1

PINK1 Antibody, BRPK Antibody, PTEN induced putative kinase 1 Antibody, PARK6 Antibody, PTEN-induced putative kinase Antibody, Protein kinase BRPK Antibody


Specifications

Target
Human PINK1
Host
Rabbit
Reactivity
Human, Monkey (tested or 100% immunogen sequence identity)
Predicted
Mouse, Bat, Dog, Hamster, Horse, Pig (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (20 µg/ml)
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
PINK1 antibody was raised against human PINK1 amino acids 484-504 (LVRALLQREASKRPSARVAAN). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%); Dog, Hamster, Elephant, Panda, Horse (95%); Mouse, Bat, Pig, Opossum (90%); Rat, Bovine, Platypus (86%); Rabbit (81%).
Epitope
aa484-504
Specificity
human PINK1 amino acids 484-504 (LVRALLQREASKRPSARVAAN)
Usage
Immunohistochemistry: LS-B1502 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B1502 was determined to be 20 ug/ml.
Presentation
TBS, pH 7.4, 0.5 mg/ml BSA, 0.02% sodium azide, 50% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Immunohistochemistry

Anti-PINK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1502 concentration 20 ug/ml.
Anti-PINK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1502 concentration 20 ug/ml.

Western blot

Western blot of PINK1 antibody LS-B1502.
Western blot of PINK1 antibody LS-B1502.

Immunohistochemistry

Anti-PINK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1502 concentration 20 ug/ml.
Anti-PINK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1502 concentration 20 ug/ml.

Western blot

Western blot of PINK1 antibody LS-B1502.
Western blot of PINK1 antibody LS-B1502.

Immunohistochemistry

Anti-PINK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1502 concentration 20 ug/ml.
Anti-PINK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1502 concentration 20 ug/ml.

Western blot

Western blot of PINK1 antibody LS-B1502.
Western blot of PINK1 antibody LS-B1502.

Immunohistochemistry

Anti-PINK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1502 concentration 20 ug/ml.
Anti-PINK1 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1502 concentration 20 ug/ml.

Western blot

Western blot of PINK1 antibody LS-B1502.
Western blot of PINK1 antibody LS-B1502.


Requested From: 
Date Requested: 6/24/2018

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