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PIN1

peptidylprolyl cis/trans isomerase, NIMA-interacting 1

Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation. Binds and targets PML and BCL6 for degradation in a phosphorylation-dependent manner.

Gene Name: peptidylprolyl cis/trans isomerase, NIMA-interacting 1
Synonyms: PIN1, DOD, PPIase Pin1, Rotamase Pin1
Target Sequences: NM_006221 NP_006212.1 Q13526

☰ Filters
Antibodies (78)
Proteins (10)
ELISA Kits (6)
Custom (2)
Over-Expression Lysate (2)
Primary (78)
Recombinant (8)
Sandwich (4)
PIN1 (94)
Human (74)
Mouse (39)
Rat (29)
Bat (4)
Bovine (7)
Chimpanzee (3)
Dog (5)
Gibbon (3)
Guinea pig (3)
Hamster (1)
Horse (4)
Monkey (11)
Pig (6)
Zebrafish (2)
IHC (24)
IHC-P (7)
WB (70)
Flo (7)
ELISA (19)
ICC (19)
IF (17)
IP (17)
Peptide-ELISA (5)
rabbit (61)
mouse (15)
goat (1)
chicken (1)
Product Group
IHCPlus (3)
IgG (43)
IgG1 (3)
IgG2b,k (1)
IgY (1)
monoclonal mc (15)
polyclonal pc (63)
2F2 (1)
3G8 (1)
855CT1.7.5 (1)
OTI4H1 (1)
96-Well Strip Plate (6)
APC (3)
APC Conjugated (5)
Azide-free (1)
Biotin Conjugated (8)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (8)
HRP Conjugated (7)
PE Conjugated (5)
Unconjugated (39)
aa2-163 (18)
aa2-165 (8)
aa30-56 (7)
pSer16 (5)
aa36-85 (4)
1-80 aa (2)
aa50-100 (2)
Ab-1619 (1)
C-Terminus (1)
N-Terminus (1)
aa1-163 (1)
aa1-50 (1)
aa113-163 (1)
aa63-80 (1)
No (94)
Cell Lysates (1)
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Human (8)
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293T Cells (1)
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Biologically active (1)
PIN1 Antibody - Anti-PIN1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PIN1 Rabbit anti-Human Polyclonal Antibody
Dog, Bovine, Human, Monkey
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$515
PIN1 Antibody - Anti-PIN1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PIN1 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$440
PIN1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$834
PIN1 Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PIN1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PIN1 Rabbit anti-Human Polyclonal (aa30-56) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
PIN1 Antibody - Western blot analysis of extracts of various cell lines.
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PIN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PIN1 Antibody - Immunohistochemistry analysis of paraffin-embedded human heart, using Pin1 (Phospho-Ser16) Antibody. The picture on the right is blocked with the phospho peptide.
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PIN1 Rabbit anti-Human Polyclonal (pSer16) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PIN1 Antibody - Anti-PIN1 antibody IHC staining of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
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PIN1 Chicken anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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PIN1 Rabbit anti-Human Polyclonal (aa30-56) Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
200 µl/$734
Select
PIN1 Rabbit anti-Human Polyclonal (aa30-56) (Biotin) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PIN1 Rabbit anti-Human Polyclonal (aa30-56) (FITC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Select
PIN1 Rabbit anti-Human Polyclonal (aa30-56) (APC) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
PIN1 Rabbit anti-Human Polyclonal (aa30-56) (PE) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
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PIN1 Rabbit anti-Human Polyclonal (aa30-56) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PIN1 Antibody - Immunohistochemical analysis of PIN1 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PIN1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Zebrafish, Pig, Rat, Mouse, Bovine, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
PIN1 Antibody - 1:200 staining human lymph node tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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PIN1 Rabbit anti-Human Polyclonal (pSer16) Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PIN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
Select
PIN1 Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PIN1 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human thyroid gland tissue using Pin1 antibody.
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PIN1 Rabbit anti-Human Polyclonal (Ab-1619) Antibody
Mouse, Rat, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
PIN1 Antibody - Western blot of Pin1 expression in COS7 whole cell lysates,The lane on the left is treated with the antigen-specific peptide.
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PIN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
PIN1 Antibody - Immunofluorescence of paraformaldehyde-fixed A549, using PIN1 antibody at 1:200 dilution.
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PIN1 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$450
PIN1 Antibody - Staining COS7 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
Select
PIN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PIN1 Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
PIN1 Mouse anti-Human Monoclonal (aa2-163) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581
PIN1 Antibody - Immunohistochemistry of paraffin-embedded human testis tissue using antibody at dilution of 1:100.
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PIN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
PIN1 Rabbit anti-Human Polyclonal (pSer16) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$328; 100 µl/$419
Viewing 1-25 of 94 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).