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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PIN1 Antibody LS‑C9614
PIN1 antibody LS-C9614 is an unconjugated rabbit polyclonal antibody to PIN1 from human, mouse and rat. Validated for IP and WB.
Antibody
Catalog
Size
Price
LS-C9614-100
100 µg (1 mg/ml)
$605

Popular PIN1 Products

Anti-PIN1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10608 concentration 5 ug/ml.
Species: Human, Monkey, Bovine, Dog
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PIN1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Species: Human
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry
Anti-PIN1 antibody IHC staining of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemistry analysis of paraffin-embedded human heart, using Pin1 (Phospho-Ser16) Antibody. The picture on the right is blocked with the phospho peptide.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemistry of paraffin-embedded rat kidney tissue.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot

Product Description

PIN1 antibody LS-C9614 is an unconjugated rabbit polyclonal antibody to PIN1 from human, mouse and rat. Validated for IP and WB.

Specifications

Target
Human PIN1
Synonyms
PIN1, DOD, PPIase Pin1, Rotamase Pin1
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
Immunogen
PIN1 antibody was raised against full-length His tagged human Pin1.
Specificity
Recognizes Pin1, Mr 18kD. Additional proteins detected in some cell lines, Mr 70kD and85kD, using high concentrations of antibody and longer exposure times. Species cross-reactivity: Human, mouse and rat.
Usage
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 0.5-2 ug/ul. Detected Pin1 in RIPA lysates from rat PC-12 and human HeLa cells. Immunoprecipitation: 4 ug.
Presentation
PBS, pH 7.6, 0.1% sodium azide, 30% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About PIN1
Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Q13526 NM_006221 NP_006212.1


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Requested From: United States
Date Requested: 10/21/2018

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