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Anti-PIK3R1 / p85 Alpha Antibody LS-C43325

Ordering

Wt. Vol. Conc. Price
- 2000 µl - $350
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PIK3R1 / p85 Alpha Antibodies

Anti-PIK3R1 / p85 Alpha Antibody (clone 6G10) IHC-plus™ LS-B8947
Mouse Monoclonal [clone 6G10] (IgG1) to Human PIK3R1 / p85 Alpha
Human
IHC - Paraffin, ICC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Unconjugated
Immunohistochemistry Image
Anti-PIK3R1 / p85 Alpha Antibody (aa3-33, Biotin) LS-C284577
Rabbit Polyclonal (IgG) to Human PIK3R1 / p85 Alpha
Human
IHC, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Biotin Conjugated

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG1) to Bovine PIK3R1 / p85 Alpha
Bovine, Human, Monkey, Mouse, Rat
Western blot, Immunoprecipitation
Unconjugated

Details

Bovine PIK3R1 / p85 Alpha
Mouse
Bovine, Human, Monkey, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Unconjugated
Unmodified

Applications

  • Western blot (1:200)
  • Immunoprecipitation (1:1)

Specificity and Use

PIK3R1 / p85 Alpha antibody was raised against balculovirus expressed (Recombinant) Bovine p85 alpha subunit of PI3 kinase.
Recognizes the SH3 domain of the p85 alpha subunit of bovine PI3 kinase, also known as Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kD regulatory subunit alpha or PtdIns-3-kinase regulatory subunit p85-alpha. p85 alpha PI3 kinase is a 724 amino acid ~85kD protein bearing a single domain, two domains and a single N-terminal domain. Multiple isoforms of the protein can be generated by alternative splicing,recognizes only those isoforms containing the SH3 domain (isoforms 1 and 4) but not those lacking the domain (isoforms 2,3 and 5). Deficiencies in the expression of the PIK3R1 gene can lead to immunodeficiency Agammaglobulinemia 7, autosomal recessive, due to the inhibition of B cell development and the developmental condition SHORT syndrome.

Packaging

Tissue culture supernatant, 0.09% sodium azide.
For research use only.

About PIK3R1 / p85 Alpha

P27986 M61906 P27986

PIK3R1 Antibody, p85 Antibody, p85 Alpha Antibody, p85-ALPHA Antibody, PI3K regulatory subunit alpha Antibody, PI3-kinase subunit p85-alpha Antibody, GRB1 Antibody

Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Requested From: United States
Date Requested: 12/4/2016

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