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Anti-PIK3C3 / VPS34 Antibody (aa22-34) LS-C188042

Catalog Size Price
LS-C188042-100 100 µg (1 mg/ml) Unavailable

Most Popular PIK3C3 / VPS34 Antibodies

Anti-PIK3C3 / VPS34 Antibody (aa770-801) LS-C163699
Rabbit Polyclonal to Human PIK3C3 / VPS34
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-PIK3C3 / VPS34 Antibody (aa24-53) LS-C163703
Rabbit Polyclonal to Human PIK3C3 / VPS34
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry Image
Anti-PIK3C3 / VPS34 Antibody (aa32-61, AP) LS-C266265
Rabbit Polyclonal (IgG) to Human PIK3C3 / VPS34
Human
IHC, ICC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
AP Conjugated
Anti-PIK3C3 / VPS34 Antibody LS-C411643
Rabbit Polyclonal to Human PIK3C3 / VPS34
Human, Mouse, Rat
IHC, Western blot
Unconjugated
Anti-PIK3C3 / VPS34 Antibody (Ser34) IHC-plus™ LS-B13741
Rabbit Polyclonal to Human PIK3C3 / VPS34
Human
IHC - Paraffin, Immunofluorescence, Western blot
Unconjugated
Immunohistochemistry - Paraffin Image

100% Guaranteed
Rabbit Polyclonal (IgG) to Human PIK3C3 / VPS34
Human, Mouse, Rat
Immunofluorescence, Western blot
Unconjugated

Details

Human PIK3C3 / VPS34
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • Immunofluorescence (1:100)
  • Western blot (2 - 4 µg/ml)

Specificity and Use

PIK3C3 / VPS34 antibody was raised against kLH conjugated synthetic peptide corresponding to amino acids 22-34 of human VPS34, The corresponding sequence is identical in mouse and rat.
aa22-34
Recognizes Phosphatidylinositol 3-kinase catalytic subunit type 3, also known as VPS34 (vacuolar protein sorting 34), PI3-kinase type 3 or PIK3C3. VPS34 is a ubiquitously expressed class III PI3K (phosphoinositide 3-kinase), and member of the PI3/PI4-kinase family, which utilizes phosphatidylinositol (PtdIn) as a substrate, and functions as the catalytic subunit of the PI3K complex. VPS34 plays a role in the transport of lysosomal enzyme precursors to lysosomes, and in endocytosis and vesicular trafficking, and has been strongly implicated as a regulator of autophagy, forming a multi-protein complex with the proautophagic tumor suppressors Beclin1/Atg6, Bif-1, and UVRAG, in the initiation of autophagosome formation. Distinct complexes of VPS34 regulates endocytic processes vital for late-stage autophagosome-lysosome fusion.

Packaging

PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About PIK3C3 / VPS34

Q8NEB9 NM_002647 NP_002638.2

PIK3C3 Antibody, HVps34 Antibody, Phosphatidylinositol 3-kinase Antibody, VPS34 Antibody, PI3-kinase type 3 Antibody, PI3K type 3 Antibody, PtdIns-3-kinase type 3 Antibody

Catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate which plays a key role in initiation and maturation of autophagosomes. Involved in the transport of lysosomal enzyme precursors to lysosomes. Required for the abcission step in cytokinesis. Required for transport from early to late endosomes.

Requested From: 
Date Requested: 10/20/2017

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