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Anti-PIAS4 / PIASY Antibody (aa44-60) LS-C608

Note: This antibody replaces LS-C38238

Ordering

Wt. Vol. Conc. Price
100 µg 200 µl 0.5 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

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Rabbit Polyclonal (IgG) to Human PIAS4 / PIASY
Human, Monkey
ICC, Western blot
Unconjugated

Details

Human PIAS4 / PIASY
Rabbit
Human, Monkey (tested or 100% immunogen sequence identity)
Mouse, Rat, Bat, Bovine, Dog, Hamster, Horse, Chicken, Xenopus (at least 90% immunogen sequence identity)
IgG Polyclonal
Protein G purified

Applications

ICC, Western blot (1 - 2 µg/ml)

Specificity and Use

PIAS4 / PIASY antibody was raised against this polyclonal antibody was developed against a mixture of synthetic peptides corresponding to amino acids 46-60 (KKIKELYETRYAKKNC) and 187-198 (YSDTSCPQEDQY) of human PIASg; GenBank no. AAD45155.1|AF164437_1. These sequences are 95% and 100% homologous in mouse and rat. Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%); Mouse, Rat, Bovine, Dog, Bat, Hamster, Elephant, Panda, Horse, Opossum, Chicken, Xenopus (93%); Marmoset (87%).
aa44-60
A mixture of synthetic peptides corresponding to amino acids 44-60 and 187-198 of human PIASg. These sequences are 95% and 100% homologous in mouse and rat.

Packaging

PBS, 0.2% gelatin, 0.05%sodium azide.
Long term: -70°C; Short term: +4°C
For research use only.

About PIAS4 / PIASY

Q8N2W9 NM_015897 NP_056981.2

PIAS4 Antibody, E3 SUMO-protein ligase PIAS4 Antibody, PIAS-gamma Antibody, ZMIZ6 Antibody, Piasg Antibody, PIASY Antibody

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53/TP53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Mediates sumoylation of CEBPA, PARK7, HERC2, MYB, TCF4 and RNF168.

Western blot

Western blot
Western blot of PIASg in Jurkat cell lysate using antibody at 2 ug/ml.
 

Requested From: United States
Date Requested: 9/30/2016

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