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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PIAS2 / PIASX Antibody (Gly24) LS‑C176342
PIASX antibody LS-C176342 is an unconjugated rabbit polyclonal antibody to PIASX (PIAS2) from human, mouse and rat. Validated for WB.
Catalog
Size
Price
LS-C176342-100
100 µl
Unavailable

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Product Description

PIASX antibody LS-C176342 is an unconjugated rabbit polyclonal antibody to PIASX (PIAS2) from human, mouse and rat. Validated for WB.
About PIAS2 / PIASX
Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing may vary depending upon the biological context and the PIAS2 isoform studied. O75928 NM_004671 NP_004662.2

PIAS2 Antibody, ARIP3 Antibody, DAB2-interacting protein Antibody, DIP Antibody, MIZ Antibody, MIZ1 Antibody, PIAS-NY protein Antibody, PIASX Antibody, PIASX-ALPHA Antibody, PIASX-BETA Antibody, SIZ2 Antibody, ZMIZ4 Antibody, E3 SUMO-protein ligase PIAS2 Antibody


Specifications

Target
Human PIAS2 / PIASX
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot
Immunogen
PIAS2 / PIASX antibody was raised against synthetic peptide around Gly24 of human PIAS2 / PIASX
Epitope
Gly24
Specificity
Human PIAS2 / PIASX
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of PIAS2 (G24) pAb in extracts from COS7 cells.
Western blot of PIAS2 (G24) pAb in extracts from COS7 cells.

Western blot

Western blot of PIAS2 (G24) pAb in extracts from COS7 cells.
Western blot of PIAS2 (G24) pAb in extracts from COS7 cells.

Western blot

Western blot of PIAS2 (G24) pAb in extracts from COS7 cells.
Western blot of PIAS2 (G24) pAb in extracts from COS7 cells.

Western blot

Western blot of PIAS2 (G24) pAb in extracts from COS7 cells.
Western blot of PIAS2 (G24) pAb in extracts from COS7 cells.


Requested From: 
Date Requested: 6/23/2018

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