PHLPP2 / PHLPPL

PH domain and leucine rich repeat protein phosphatase 2

Protein phosphatase that mediates dephosphorylation of 'Ser-473' of AKT1, 'Ser-660' of PRKCB isoform beta-II and 'Ser-657' of PRKCA. AKT1 regulates the balance between cell survival and apoptosis through a cascade that primarily alters the function of transcription factors that regulate pro- and antiapoptotic genes. Dephosphorylation of 'Ser-473' of AKT1 triggers apoptosis and decreases cell proliferation. Also controls the phosphorylation of AKT3. Dephosphorylation of PRKCA and PRKCB leads to their destabilization and degradation. Inhibits cancer cell proliferation and may act as a tumor suppressor.

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Products

Antibodies (9)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (9)

Recombinant (1)

Target

PHLPP2 / PHLPPL (12)

Reactivity

Human (9)

Mouse (3)

Rat (1)

Application

IHC (6)

IHC-P (4)

WB (9)

Flo (1)

ELISA (4)

ICC (1)

IF (2)

IP (2)

Peptide-ELISA (2)

Host

rabbit (8)

goat (1)

Product Group

IHCPlus (2)

Isotype

Ig (1)

IgG (5)

Clonality

polyclonal pc (9)

Format

Unconjugated (9)

Epitope

C-Terminus (1)

aa1275-C-term (1)

aa1295-1323 (1)

aa1307-1320 (1)

aa4-31 (1)

Publications

No (12)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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IHC-plus™ PHLPP2 / PHLPPL Antibody (C-Terminus) LS-B6340

(4.0) Rating

Antibody:

PHLPP2 / PHLPPL Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, IHC-P, IP, WB

Format:

Unconjugated

Price:

50 µl/$485

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IHC-plus™ PHLPP2 / PHLPPL Antibody LS-B8861

(4.0) Rating

Antibody:

PHLPP2 / PHLPPL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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PHLPP2 / PHLPPL Antibody LS-C754384

Antibody:

PHLPP2 / PHLPPL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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PHLPP2 / PHLPPL Antibody (aa1295-1323) LS-C163578

Antibody:

PHLPP2 / PHLPPL Rabbit anti-Human Polyclonal (aa1295-1323) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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PHLPP2 / PHLPPL Antibody LS-C750939

Antibody:

PHLPP2 / PHLPPL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$466

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PHLPP2 / PHLPPL Antibody (aa4-31) LS-C97139

Antibody:

PHLPP2 / PHLPPL Rabbit anti-Human Polyclonal (aa4-31) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

400 µl/$393

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PHLPP2 / PHLPPL Antibody (aa1275-C-term) LS-C287530

Antibody:

PHLPP2 / PHLPPL Rabbit anti-Human Polyclonal (aa1275-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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PHLPP2 / PHLPPL Antibody LS-C803101

Antibody:

PHLPP2 / PHLPPL Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PHLPP2 / PHLPPL Antibody (aa1307-1320) LS-C55275

Antibody:

PHLPP2 / PHLPPL Goat anti-Human Polyclonal (aa1307-1320) Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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Human PHLPP2 / PHLPPL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93230

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

146.6 kDa

Price:

20 µg/$215

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Human PHLPP2 / PHLPPL Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72670

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

146.6 kDa

Price:

20 µg/$1,107

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PHLPP2 / PHLPPL Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113524

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

146.6 kDa

Price:

100 µg/$710

Viewing 1-12 of 12 product results

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