PHKB

phosphorylase kinase, beta

Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency of liver and muscle. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. Two pseudogenes have been found on chromosomes 14 and 20, respectively.

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Products

Antibodies (13)

Proteins (6)

ELISA Kits (1)

Type

Cell-Based (1)

Over-Expression Lysate (4)

Primary (13)

Recombinant (2)

Target

PHKB (20)

Reactivity

Human (14)

Mouse (10)

Rat (3)

Monkey (1)

Application

IHC (2)

IHC-P (1)

WB (12)

ELISA (5)

IF (1)

IP (2)

Peptide-ELISA (2)

Host

rabbit (12)

mouse (1)

Isotype

IgG (9)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (12)

Clone

2E9 (1)

Format

96-Well Microplate (1)

Unconjugated (13)

Epitope

630-710 aa, Internal (1)

Internal (1)

aa650-700 (1)

aa661-710 (1)

aa699-744 (1)

Publications

No (20)

Sample Type

Adherent Cell Cultures (1)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (5)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (3)

Wheat Germ Extract (1)

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PHKB Antibody (aa661-710) LS-C119198

Antibody:

PHKB Rabbit anti-Human Polyclonal (aa661-710) Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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PHKB Antibody LS-C667653

Antibody:

PHKB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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PHKB Antibody LS-C676259

Antibody:

PHKB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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PHKB Antibody LS-C808723

Antibody:

PHKB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PHKB Antibody (clone 2E9) LS-C197893

Antibody:

PHKB Mouse anti-Human Monoclonal (2E9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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PHKB Antibody (630-710 aa, Internal) LS-C385469

Antibody:

PHKB Rabbit anti-Human Polyclonal (630-710 aa, Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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PHKB Antibody LS-C823129

Antibody:

PHKB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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PHKB Antibody (aa650-700) LS-C762400

Antibody:

PHKB Rabbit anti-Human Polyclonal (aa650-700) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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PHKB Antibody LS-C658776

Antibody:

PHKB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

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PHKB Antibody (aa699-744) LS-C313879

Antibody:

PHKB Rabbit anti-Human Polyclonal (aa699-744) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

Select

PHKB Antibody LS-C769019

Antibody:

PHKB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

PHKB Antibody LS-C409558

Antibody:

PHKB Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

PHKB Antibody (Internal) LS-C352650

Antibody:

PHKB Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$299

Select

PHKB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123282

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

124.7 kDa

Price:

100 µg/$710

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Human PHKB Protein (Recombinant GST, N-terminus) (aa984-1093) - LS-G59591

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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PHKB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120749

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.6 kDa

Price:

100 µg/$494

Select

Mouse/Human PHKB (Cell-Based ELISA) ELISA Kit - LS-F3276

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

Select

Human PHKB Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66584

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.6 kDa

Price:

20 µg/$1,107

Select

Human PHKB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78043

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

124.7 kDa

Price:

20 µg/$215

Select

Human PHKB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78044

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

123.6 kDa

Price:

20 µg/$150

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