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PHB / Prohibitin

prohibitin

Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.

Gene Name: prohibitin
Synonyms: PHB, PHB1, Prohibitin
Target Sequences: NM_002634 NP_002625.1 P35232

Publications (4)

1
Coupling of the de novo fatty acid biosynthesis and lipoylation pathways in mammalian mitochondria. Witkowski A, Joshi AK, Smith S. The Journal of biological chemistry. 2007 282:14178-85. [PubMed:17374604]
2
Up-regulation of the peroxiredoxin-6 related metabolism of reactive oxygen species in skeletal muscle of mice lacking neuronal nitric oxide synthase. Da Silva-Azevedo L, Jhne S, Hoffmann C, Stalder D, Heller M, Pries AR, Zakrzewicz A, Baum O. The Journal of physiology. 2009 587:655-68. [PubMed:19047200] [PMC:PMC2670087]
3
Circulating levels of mitochondrial uncoupling protein 2, but not prohibitin, are lower in humans with type 2 diabetes and correlate with brachial artery flow-mediated dilation. Kakarla M, Puppala VK, Tyagi S, Anger A, Repp K, Wang J, Ying R, Widlansky ME. Cardiovascular Diabetology. 2019 November;18:148. [Full Text Article] [PubMed:31706320] [PMC:PMC6842161]
4
A proteomic view of isoproterenol induced cardiac hypertrophy: prohibitin identified as a potential biomarker in rats. Chowdhury D, Tangutur AD, Khatua TN, Saxena P, Banerjee SK, Bhadra MP. Journal of translational medicine. 2013 11:130. (IHC, WB; Human) [Full Text Article] [PubMed:23706090] [PMC:PMC3667141] Related Antibodies: LS-C29731.
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☰ Filters
Antibodies (56)
ELISA Kits (18)
Proteins (8)
Competitive EIA (1)
Over-Expression Lysate (2)
Primary (56)
Recombinant (6)
Sandwich (14)
Sandwich CLIA (3)
PHB / Prohibitin (82)
Human (61)
Mouse (26)
Rat (25)
Bat (7)
Bovine (7)
Chicken (6)
Chimpanzee (6)
Dog (6)
Gibbon (6)
Guinea pig (8)
Hamster (6)
Horse (7)
Monkey (10)
Non-Human Primate (1)
Pig (8)
Porcine (1)
Rabbit (8)
Sheep (1)
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IHC (31)
IHC-P (19)
WB (53)
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IP (2)
Peptide-ELISA (1)
rabbit (44)
mouse (12)
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monoclonal mc (12)
polyclonal pc (44)
1215CT487.109.106 (1)
5H7 (2)
PHB/1881 (3)
PHB/1882 (3)
12 x 8-Well Microstrips (2)
96-Well Strip Plate (16)
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Azide-free (4)
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PHB / Prohibitin Antibody - PHB / Prohibitin antibody ARP32807_P050-NP_002625-PHB (prohibitin) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human stomach.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PHB / Prohibitin Rabbit anti-Human Polyclonal (aa203-252) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
PHB / Prohibitin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
PHB / Prohibitin Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PHB / Prohibitin Mouse anti-Human Monoclonal (5H7) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
PHB / Prohibitin Antibody - Anti-PHB / Prohibitin antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PHB / Prohibitin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
PHB / Prohibitin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.391 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PHB / Prohibitin Antibody - Anti-PHB / Prohibitin antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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PHB / Prohibitin Rabbit anti-Human Polyclonal (aa222-272) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PHB / Prohibitin Antibody - Anti-PHB / Prohibitin antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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PHB / Prohibitin Rabbit anti-Human Polyclonal (aa92-121) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
PHB / Prohibitin Antibody - Prohibitin Antibody in Immunohistochemistry (IHC)
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PHB / Prohibitin Mouse anti-Human Monoclonal (5H7) Antibody
Mouse, Rat, Non-Human Primate, Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$541
PHB / Prohibitin Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded rectum cancer tissues with DAB staining using Prohibitin Monoclonal Antibody.
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PHB / Prohibitin Mouse anti-Human Monoclonal Antibody
Rat, Human, Monkey
ELISA, Flo, IF, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
PHB / Prohibitin Antibody - Detection of Human Prohibitin by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-Prohibitin used at a dilution of 1:250. Epitope Retrieval Buffer-High pH (IHC-101J) was substituted for Epitope Retrieval Buffer-Reduced pH.
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PHB / Prohibitin Rabbit anti-Human Polyclonal (aa222-272) Antibody
Human
IHC, IHC-P
Unconjugated
2.5 µg/$295; 100 µl/$532
PHB / Prohibitin Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PHB antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PHB / Prohibitin Rabbit anti-Human Polyclonal (aa89-117) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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PHB / Prohibitin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
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PHB / Prohibitin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
PHB / Prohibitin Antibody - Anti-Prohibitin antibody, IHC(P): Human Lung Cancer Tissue
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PHB / Prohibitin Rabbit anti-Human Polyclonal (aa240-256) Antibody
Chicken, Sheep, Bovine, Rat, Pig, Horse, Bat, Rabbit, Mouse, Guinea pig, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PHB / Prohibitin Antibody - Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PHB / Prohibitin Rabbit anti-Human Polyclonal (aa182-211) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
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PHB / Prohibitin Mouse anti-Rat Monoclonal Antibody
Chicken, Rat, Pig, Mouse, Human
IF, IHC, IHC-P, IP, WB
Unconjugated
500 µl/$906
PHB / Prohibitin Protein - 12.5% SDS-PAGE of human PHB stained with Coomassie Blue
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Wheat Germ Extract
GST
55.66 kDa
10 µg/$479; 25 µg/$670
PHB / Prohibitin Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using PHB Polyclonal Antibody at dilution of 1:30.
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PHB / Prohibitin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PHB / Prohibitin Antibody - Immunohistochemistry of paraffin-embedded Human liver cancer using PHB Polyclonal Antibody at dilution of 1:40.
Select
PHB / Prohibitin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
PHB / Prohibitin Rabbit anti-Human Polyclonal (aa92-121) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
PHB / Prohibitin Rabbit anti-Human Polyclonal (aa92-121) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PHB / Prohibitin Rabbit anti-Human Polyclonal (aa92-121) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
PHB / Prohibitin Antibody - IHC testing of FFPE human liver tissue with Prohibitin antibody (clone PHB/1881). Required HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
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PHB / Prohibitin Mouse anti-Human Monoclonal (PHB/1881) Antibody
Human
ELISA, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
PHB / Prohibitin Antibody - IHC testing of FFPE human liver tissue with Prohibitin antibody (clone PHB/1881). Required HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
Select
PHB / Prohibitin Mouse anti-Human Monoclonal (Azide-free, BSA-free) (PHB/1881) Antibody
Human
ELISA, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
PHB / Prohibitin Antibody - Immunohistochemistry of paraffin-embedded human kidney tissue using PHB Antibody at dilution of 1:20
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PHB / Prohibitin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
Viewing 1-25 of 82 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).