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PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

PFKFB1 is a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.

Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Synonyms: PFKFB1, 6PF-2-K/Fru-2,6-P2ase 1, HL2K, PFK/FBPase 1, PFRX, F6PK
Target Sequences: NM_002625 NP_002616.2 P16118

☰ Filters
Antibodies (29)
Proteins (8)
Over-Expression Lysate (2)
Primary (29)
Recombinant (6)
PFKFB1 (37)
Human (29)
Mouse (17)
Rat (10)
Bat (6)
Bovine (6)
Chicken (3)
Chimpanzee (3)
Dog (6)
Gibbon (6)
Guinea pig (6)
Horse (6)
Monkey (6)
Pig (6)
Rabbit (3)
Zebrafish (6)
IHC (17)
IHC-P (3)
WB (28)
ELISA (15)
IF (2)
Peptide-ELISA (3)
rabbit (29)
IgG (18)
polyclonal pc (29)
APC Conjugated (2)
Azide-free (4)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (13)
aa13-43 (7)
aa259-289 (7)
C-Terminus (4)
aa335-384 (4)
380-460 aa, C-terminal (1)
Glu442 (1)
aa406-455 (1)
No (37)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (7)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
PFKFB1 Antibody - Staining HeLa cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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PFKFB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PFKFB1 Antibody - Western blot of PFK-2 liv antibody
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PFKFB1 Rabbit anti-Human Polyclonal (380-460 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PFKFB1 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody, diluted at 1/600, was used as secondary antibody.
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PFKFB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PFKFB1 Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PFKFB1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PFKFB1 Rabbit anti-Human Polyclonal (aa259-289) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PFKFB1 Antibody - Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PFKFB1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PFKFB1 Rabbit anti-Human Polyclonal (aa13-43) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PFKFB1 Antibody - IHC of PFK-2 liv (E442) pAb in paraffin-embedded human liver carcinoma tissue.
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PFKFB1 Rabbit anti-Human Polyclonal (Glu442) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
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PFKFB1 Rabbit anti-Human Polyclonal (aa259-289) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa259-289) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa259-289) (Azide-free) Antibody
Human
ELISA, IHC, WB
Unconjugated, Azide-free
200 µl/$734
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa259-289) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa259-289) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa259-289) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa13-43) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa13-43) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa13-43) (Azide-free) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated, Azide-free
200 µl/$734
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa13-43) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa13-43) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
PFKFB1 Rabbit anti-Human Polyclonal (aa13-43) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PFKFB1 Antibody - Immunohistochemistry of paraffin-embedded Human brain using PFKFB1 Polyclonal Antibody at dilution of 1:60.
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PFKFB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PFKFB1 Antibody - Western blot analysis of extracts from HUVEC cells and Jurkat cells, using PFKFB1 antibody.
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PFKFB1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PFKFB1 Antibody - Western blot analysis of lysates from HUVEC cells and Jurkat cells, using PFKFB1 Antibody. The lane on the right is blocked with the synthesized peptide.
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PFKFB1 Rabbit anti-Human Polyclonal (aa406-455) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PFKFB1 Antibody - PFKFB1 antibody Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PFKFB1 Rabbit anti-Human Polyclonal (aa335-384) Antibody
Human
WB
Unconjugated
100 µl/$424
PFKFB1 Antibody - PFKFB1 antibody Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PFKFB1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
PFKFB1 Antibody - PFKFB1 antibody Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PFKFB1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Zebrafish, Pig, Horse, Bat, Dog, Guinea pig, Bovine, Human, Monkey, Gibbon
WB
HRP Conjugated
100 µl/$469
PFKFB1 Antibody - PFKFB1 antibody Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PFKFB1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Zebrafish, Pig, Horse, Bat, Dog, Guinea pig, Bovine, Human, Monkey, Gibbon
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 37 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).