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Peripherin

Peripherin is a cytoskeletal protein found in neurons of the peripheral nervous system. The encoded protein is a type III intermediate filament protein with homology to other cytoskeletal proteins such as desmin, and is a different protein that the peripherin found in photoreceptors. Mutations in this gene have been associated with susceptibility to amyotrophic lateral sclerosis.

Gene Name: Peripherin
Synonyms: PRPH, NEF4, Neurofilament 4 (57kD), Peripherin, PRPH1, Neurofilament 4
Target Sequences: NM_006262 NP_006253.2 P41219

Publications (4)

1
Distribution of plectin, an intermediate filament-associated protein, in the adult rat central nervous system. Errante LD, Wiche G, Shaw G. Journal of neuroscience research. 1994 37:515-28. [PubMed:8021973]
2
Viral delivery of NR2D subunits reduces Mg2+ block of NMDA receptor and restores NT-3-induced potentiation of AMPA-kainate responses in maturing rat motoneurons. Arvanian VL, Bowers WJ, Petruska JC, Motin V, Manuzon H, Narrow WC, Federoff HJ, Mendell LM. Journal of neurophysiology. 2004 92:2394-404. [PubMed:15152019]
3
Motor axon guidance of the mammalian trochlear and phrenic nerves: dependence on the netrin receptor Unc5c and modifier loci. Burgess RW, Jucius TJ, Ackerman SL. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2006 26:5756-66. [PubMed:16723533]
4
Progesterone withdrawal promotes remodeling processes in the nonpregnant mouse cervix. Yellon SM, Burns AE, See JL, Lechuga TJ, Kirby MA. Biology of reproduction. 2009 81:6-Jan. [PubMed:19228593] [PMC:PMC3093982]
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☰ Filters
Antibodies (58)
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Peripherin (70)
Human (54)
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Peripherin Antibody - Anti-PRPH / Peripherin antibody IHC of human small intestine, myenteric plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Neuroscience
Peripherin Mouse anti-Human Monoclonal (aa374-471) (3B3) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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Peripherin Mouse anti-Rat Monoclonal (8G2) Antibody
Mammal, Human
ELISA, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µl/$807
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Peripherin Rabbit anti-Human Polyclonal (aa1-260) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
Peripherin Antibody - Western blot of PRPH antibody
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Peripherin Rabbit anti-Human Polyclonal (390-470 aa, C-terminal) Antibody
Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Peripherin ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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Peripherin Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Mouse, Bovine, Rat, Pig, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µl/$884
Peripherin Antibody - Western blot of rat cerebellar lysate showing specific immunolabeling of the ~57k peripherin protein.
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Peripherin Chicken anti-Rat Polyclonal Antibody
Rat, Mammal
IF, WB
Unconjugated
100 µl/$436
Peripherin Antibody - Anti-PRPH / Peripherin antibody IHC of human nerve. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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Peripherin Rabbit anti-Human Polyclonal (aa421-470) Antibody
Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Peripherin Antibody - 1:100 staining human colon carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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Peripherin Rabbit anti-Human Polyclonal (aa445-470) Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Peripherin Antibody - Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-PRPH mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.0) at 110C for 10 min. (1:200)
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Peripherin Mouse anti-Human Monoclonal (UMAB202) Antibody
Human
IF, IHC, WB
Unconjugated
100 µl/$493
Peripherin Antibody - Immunohistochemical staining of paraffin-embedded Human Ovary tissue using anti-PRPH mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer. (pH8.0) at 110C for 10 min. (1:200)
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Peripherin Mouse anti-Human Monoclonal (Carrier-free) (UMAB202) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$539
Peripherin Antibody - Human Colon, Myenteric Plexus: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Neuroscience
Peripherin Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$440
Peripherin Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PRPH mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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Peripherin Mouse anti-Human Monoclonal (OTI2D5) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
Peripherin Antibody - Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PRPH mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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Peripherin Mouse anti-Human Monoclonal (Carrier-free) (OTI2D5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Peripherin Antibody - IHC of paraffin-embedded Human colon tissue using anti-PRPH mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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Peripherin Mouse anti-Human Monoclonal (OTI1E10) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$434
Peripherin Antibody - Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PRPH mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min,
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Peripherin Mouse anti-Human Monoclonal (Carrier-free) (OTI1E10) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Peripherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
Peripherin ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$854
Peripherin Antibody - A neuron in a rat cortical neuron culture which stains strongly for peripherin with Peripherin antibody (red). A minority of cells in such cultures are strongly peripherin positive. In some cases they also stain for other neurofilament subunits, but this particular cell shows very little staining for NF-L using a rabbit polyclonal antibody (green). Blue is the DNA stain DAPI.
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Peripherin Mouse anti-Human Monoclonal (8G2) Antibody
Mammal
ICC, IF, WB
Unconjugated
500 µl/$376
Peripherin Antibody - IHC of paraffin-embedded Human colon tissue using anti-PRPH mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
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Peripherin Mouse anti-Human Monoclonal (OTI3F4) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
Peripherin Antibody - Mixed neuron/glia cultures from newborn rat brain stained with MCS-7C5 antibody to peripherin (green) and chicken polyclonal antibody to phosphorylated NF-H CPCA-NF-H (red channel). A class of large neurons, like the one in the middle of this image, contain peripherin, while the majority of neurons and their processes contain NF-L and not peripherin. Interestingly, the peripherin positive cells often contain a cytoplasmic inclusion next to the nucleus which stains for both peripherin and NF-L, and so appears golden in this kind of image. The blue channel reveals the localization of DNA.
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Peripherin Rabbit anti-Human Polyclonal Antibody
Human
ICC, IHC, WB
Unconjugated
100 µl/$376
Peripherin Antibody - Immunostaining of cultured newborn rat neurons and glia showing peripherin in green and neurofilament L in red.
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Peripherin Mouse anti-Rat Monoclonal Antibody
Rat, Mammal
ICC, IF, WB
Unconjugated
100 µl/$469
Peripherin Antibody - Peptide - + Immunohistochemical analysis of paraffin-embedded human brain tissue using Peripherin antibody.
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Peripherin Rabbit anti-Human Polyclonal (aa455-470) Antibody
Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
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Peripherin Chicken anti-Human Polyclonal Antibody
Human
ICC, IHC, WB
Unconjugated
200 µl/$725
Peripherin Antibody - Immunohistochemistry of paraffin-embedded human thyroid tissue at dilution 1:100
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Peripherin Rabbit anti-Human Polyclonal (aa1-260) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
Viewing 1-25 of 70 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).