Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Protein A/G purified
Specificity and Use
Peptide Histidine-Methionine (PHM).
Recognizes Peptide Histidine-Methionine (PHM). Binds human PHM and cross-reacts with PACAP (approximately 12%; incomplete, non-parallel inhibition). Does not cross-react with GLP-1, GLP-2, VIP or glucagon. Binds free PHM in solution. The ELISA dilution guideline of 1:2000 applies to PHM coated directly at 2 ug/ml. For glutaraldehyde-linked PHM-ovalbumin (molar ratio 4:1) coated at 1 ug/ml the dilution is 1:30000.