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Anti-PELP1 Antibody (aa1000-1050) LS-C56964

Note: This antibody replaces LS-C74229
Catalog Size Price
LS-C56964-50 50 µg (1 mg/ml) Unavailable

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32 PELP1 Antibodies

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Anti-PELP1 Antibody (aa1000-1050) LS-C56964
Rabbit Polyclonal to Human PELP1
Human, Mouse
Western blot, Immunoprecipitation
Western blot Image
Anti-PELP1 Antibody (aa751-779) LS-C323934
Rabbit Polyclonal (IgG) to Human PELP1
Human, Mouse
IHC, Western blot, ELISA
Anti-PELP1 Antibody LS-C332411
Rabbit Polyclonal (IgG) to Human PELP1
Human, Mouse, Rat
IHC, Western blot
Immunohistochemistry Image
Anti-PELP1 Antibody (aa1000-1050) IHC-plus™ LS-B13977
Rabbit Polyclonal (IgG) to Human PELP1
Human, Mouse
IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation
Immunohistochemistry - Paraffin Image
Anti-PELP1 Antibody (aa1000-1050) IHC-plus™ LS-B14214
Rabbit Polyclonal (IgG) to Human PELP1
Human, Mouse
IHC - Paraffin, Immunofluorescence
Immunohistochemistry - Paraffin Image

100% Guaranteed
Rabbit Polyclonal to Human PELP1
Human, Mouse
Western blot, Immunoprecipitation


Human PELP1
Human, Mouse (tested or 100% immunogen sequence identity)
Affinity purified


  • Western blot (1:2500 - 1:10000)
  • Immunoprecipitation

Specificity and Use

PELP1 antibody was raised against synthetic peptide corresponding to an epitope within amino acid residues 1000-1050 of human MNAR (AAN41255.1).
Recognizes MNAR (modulator of non-genomic activity of estrogen receptor), otherwise known as PELP1 (proline-, glutamic acid-, and leucine-rich protein-1), a phosphoprotein and novel steroid co-activator of the estrogen receptor (ER), which plays a role in E2-mediated cell cycle progression through interaction with the pRb pathway. MNAR acts as a transcriptional corepressor for nuclear receptors and can interact with chromatin-modifying complex components CBP (CRE-binding protein), histone deacetylase 2 and MTA (metastasis-associated protein)1. MNAR is a src SH2-binding protein which modulates the interaction of the ER to c-Src, leading to MAPK activation. Other properties of MNAR include interaction with PI3K, STAT3, and EGF, and studies have shown the deregulation of MNAR in breast tumors and endometrial cancers.
Western Blot: LS-C56964 detects a band of approximately 160-170kD in HeLa whole cell lysates.


Tris-citrate/Phosphate buffered saline, 0.09% sodium azide.
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About PELP1

Q8IZL8 BC002875 AAH02875.2

PELP1 Antibody, MNAR Antibody, Transcription factor HMX3 Antibody, p160 Antibody

Coactivator of estrogen receptor-mediated transcription and a corepressor of other nuclear hormone receptors and sequence-specific transcription factors. Plays a role in estrogen receptor (ER) genomic activity when present in the nuclear compartment by activating the ER target genes in a hormonal stimulation dependent manner. Can facilitate ER non-genomic signaling via SRC and PI3K interaction in the cytosol. Plays a role in E2-mediated cell cycle progression by interacting with RB1.

Western blot

Western blot
Detection of human MNAR in whole cell lysates from HeLa cells by immunoprecipitation using 3 ug/mg lysate of Rabbit anti-Human MNAR (LS-C56964). MNAR was also immunoprecipitated with an antibody recognizing a different region within human MNAR. Human MNAR was also detected by Western Blotting in whole cell lysates of HeLa and 293T cells using Rabbit anti-Human MNAR (LS-C56964).

Requested From: 
Date Requested: 2/19/2018

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