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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PECAM‑1 / CD31 Antibody (RPE) LS‑C43870
Note: This antibody replaces LS-C57472
Antibody
CD31 antibody LS-C43870 is an RPE-conjugated mouse monoclonal antibody to CD31 (PECAM-1) from human and pig. Validated for Flow.
Catalog
Size
Price
LS-C43870-100
100 tst
Unavailable

Popular PECAM-1 / CD31 Products

IHC of rat spleen cryosection with Mouse anti-Rat CD31 (LS-C43483).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Species: Rat
Applications: IHC, IHC - Frozen, Western blot, Flow Cytometry, ELISA
Anti-CD31 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2364 concentration 5 ug/ml.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, ELISA
Anti-CD31 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4737 concentration 10 ug/ml.
Species: Mouse, Human
Applications: IHC, IHC - Paraffin
Anti-CD31 antibody IHC of human tonsil, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5577 dilution 1:100.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Anti-PECAM-1 / CD31 antibody IHC staining of human uterus, endometrium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10502 concentration 20 ug/ml.
Species: Human, Dog
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Flow Cytometry

Product Description

CD31 antibody LS-C43870 is an RPE-conjugated mouse monoclonal antibody to CD31 (PECAM-1) from human and pig. Validated for Flow.
About PECAM-1 / CD31
Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. P16284 NM_000442 NP_000433.4

PECAM1 Antibody, CD31 Antibody, CD31 antigen Antibody, EndoCAM Antibody, PECA1 Antibody, PECAM-1 Antibody, GPIIA Antibody


Specifications

Target
Pig PECAM-1 / CD31
Host
Mouse
Reactivity
Pig, Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
R. Phycoerythrin
Purification
Affinity purified
Modifications
Unmodified
Applications
  • Flow Cytometry (1:1)
Immunogen
PECAM-1 / CD31 antibody was raised against porcine CD31/human IgGFc fusion protein.
Specificity
Recognizes porcine CD31, also known as Platelet endothelial cell adhesion molecule (PECAM-1). CD31 is constitutively expressed by platelets, monocytes and some lymphocytes, it is expressed by endothelial cells at a level, an order of magnitude greater that of other cell types. The extracellular region contains six Ig-like domains. Clone LCI-4 is cross reactive with human CD31 and binds to the 5th extracellular Ig domain, proximal to the transmembrane region as demonstrated by human CD31 domain deletion mutant protein binding studies. Immunoprecipitates a protein of ~130 kD from lysates of porcine aortic endothelial cells and is strongly expressed at cell junctions.
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 100 ul of lysed whole blood or 10^6 cells in 100 ul. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
Lyophilized, PBS, 0.09% sodium azide, 5% sucrose
Reconstitution
100 tst Reconstitute with 1ml distilled water.
Storage
Lyophilized powder may be stored at 4°C before opening. DO NOT FREEZE! Aliquot and store at 4°C. Stable at 4°C as an undiluted liquid for 6 months. Dilute only prior to immediate use.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/21/2018

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