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Anti-PECAM-1 / CD31 Antibody (clone WM59) LS-C40811

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $215
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular PECAM-1 / CD31 Antibodies

Anti-PECAM-1 / CD31 Antibody IHC-plus™ LS-B4737
Rabbit Polyclonal to Mouse PECAM-1 / CD31
Mouse, Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-PECAM-1 / CD31 Antibody (aa18-590) LS-C150165
Goat Polyclonal (IgG) to Mouse PECAM-1 / CD31
Mouse
IHC, Western blot, Flow Cytometry
Unconjugated
Immunocytochemistry Image

100% Guaranteed 100% Guaranteed Publications Publications (3)
Mouse Monoclonal [clone WM59] (IgG1) to Human PECAM-1 / CD31
Human, Baboon, Monkey
IHC - Frozen, Immunofluorescence, Flow Cytometry
Unconjugated

Details

Human PECAM-1 / CD31
Mouse
Human, Baboon, Monkey (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [WM59]
Unconjugated
Affinity purified
Unmodified

Applications

  • IHC - Frozen
  • Immunofluorescence
  • Flow Cytometry

Specificity and Use

PECAM-1 / CD31 antibody was raised against human myeloid leukemia cells
Clone WM59 has been reported to recognize the D2 extracellular portion of CD31

Packaging

PBS, pH 7.2, 0.09% sodium azide.
+4°C, avoid freezing
For research use only.

Publications (3)

1
Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium. MacFadyen JR, Haworth O, Roberston D, Hardie D, Webster MT, Morris HR, Panico M, Sutton-Smith M, Dell A, van der Geer P, Wienke D, Buckley CD, Isacke CM. FEBS letters. 2005 579:2569-75. [PubMed:15862292]
2
Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Nagano M, Yamashita T, Hamada H, Ohneda K, Kimura K, Nakagawa T, Shibuya M, Yoshikawa H, Ohneda O. Blood. 2007 110:151-60. [PubMed:17379743]
3
Targeting tumor-associated endothelial cells: anti-VEGFR2 immunoliposomes mediate tumor vessel disruption and inhibit tumor growth. Wicki A, Rochlitz C, Orleth A, Ritschard R, Albrecht I, Herrmann R, Christofori G, Mamot C. Clinical cancer research : an official journal of the American Association for Cancer Research. 2012 18:454-64. [PubMed:22065082]

About PECAM-1 / CD31

P16284 NM_000442 NP_000433.4

PECAM1 Antibody, CD31 Antibody, CD31 antigen Antibody, EndoCAM Antibody, PECA1 Antibody, PECAM-1 Antibody, GPIIA Antibody

Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes.

Flow Cytometry

Flow Cytometry
Human peripheral blood lymphocytes, monocytes and granulocytes stained with purified WM59, then detected with anti-mouse IgG FITC.
 

Requested From: United States
Date Requested: 12/11/2016

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