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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PEA15 / PEA‑15 Antibody (Asp110) LS‑C176448
PEA-15 antibody LS-C176448 is an unconjugated rabbit polyclonal antibody to PEA-15 (PEA15) from human, mouse and rat. Validated for IF, IHC and WB.
Catalog
Size
Price
LS-C176448-100
100 µl
Unavailable

Popular PEA15 / PEA-15 Products

Antibody
Species: Human, Mouse, Rat
Applications: Western blot, Immunoprecipitation, ELISA
Antibody
Species: Human, Mouse, Rat
Applications: Western blot
Anti-PEA15 antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6997 dilution 1:100.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Immunohistochemical analysis of PEA15 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, ICC, Immunofluorescence, Western blot, Immunoprecipitation
Immunohistochemistry of paraffin-embedded human kidney tissue at dilution 1:100
Species: Human
Applications: IHC, Immunofluorescence, Western blot, ELISA

Product Description

PEA-15 antibody LS-C176448 is an unconjugated rabbit polyclonal antibody to PEA-15 (PEA15) from human, mouse and rat. Validated for IF, IHC and WB.
About PEA15 / PEA-15
Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface. Q15121 NM_003768 NP_003759.1

PEA15 Antibody, MAT1 Antibody, HMAT1 Antibody, PEA-15 Antibody, HUMMAT1H Antibody, MAT1H Antibody, PED Antibody


Specifications

Target
Human PEA15 / PEA-15
Host
Rabbit
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin
  • Immunofluorescence
  • Western blot
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
PEA15 / PEA-15 antibody was raised against synthetic peptide around Asp110 of human PEA15
Epitope
Asp110
Specificity
Human PEA15
Presentation
PBS, pH 7.2, 0.05% sodium azide
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

IHC of PEA-15 (D110) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of PEA-15 (D110) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of PEA-15 (D110) pAb in extracts from Jurkat cells treated with PMA 125ng/ml 30'.
Western blot of PEA-15 (D110) pAb in extracts from Jurkat cells treated with PMA 125ng/ml 30'.

Immunohistochemistry

IHC of PEA-15 (D110) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of PEA-15 (D110) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of PEA-15 (D110) pAb in extracts from Jurkat cells treated with PMA 125ng/ml 30'.
Western blot of PEA-15 (D110) pAb in extracts from Jurkat cells treated with PMA 125ng/ml 30'.

Immunohistochemistry

IHC of PEA-15 (D110) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of PEA-15 (D110) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of PEA-15 (D110) pAb in extracts from Jurkat cells treated with PMA 125ng/ml 30'.
Western blot of PEA-15 (D110) pAb in extracts from Jurkat cells treated with PMA 125ng/ml 30'.

Immunohistochemistry

IHC of PEA-15 (D110) pAb in paraffin-embedded human colon carcinoma tissue.
IHC of PEA-15 (D110) pAb in paraffin-embedded human colon carcinoma tissue.

Western blot

Western blot of PEA-15 (D110) pAb in extracts from Jurkat cells treated with PMA 125ng/ml 30'.
Western blot of PEA-15 (D110) pAb in extracts from Jurkat cells treated with PMA 125ng/ml 30'.


Requested From: 
Date Requested: 6/19/2018

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