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PDZD3

PDZ domain containing 3

Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]).

Gene Name: PDZ domain containing 3
Synonyms: PDZD3, IKEPP, NHERF-4, PDZ domain containing 2, PDZK2, NaPi-Cap2, NHERF4, PDZ domain containing 3
Target Sequences: NM_024791

Publications (1)

1
USP2-45 Is a Circadian Clock Output Effector Regulating Calcium Absorption at the Post-Translational Level. Pouly D, Chenaux S, Martin V, Babis M, Koch R, Nagoshi E, Katanaev VL, Gachon F, Staub O. PloS one. 2016 11:e0145155. (IHC; Human) [Full Text Article] [PubMed:26756164] [PMC:PMC4710524]

☰ Filters
Antibodies (25)
Proteins (5)
Over-Expression Lysate (4)
Primary (25)
Recombinant (1)
PDZD3 (30)
Human (25)
Mouse (3)
Rat (2)
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IHC (3)
IHC-P (3)
WB (22)
ELISA (13)
rabbit (25)
Product Group
IHCPlus (2)
IgG (13)
polyclonal pc (25)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (11)
aa258-285 (7)
aa105-154 (4)
aa315-364 (4)
C-Terminus (1)
aa119-435 (1)
No (30)
GST (1)
Myc-DDK (Flag) (4)
Human (3)
293T Cells (2)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
PDZD3 Antibody - Anti-PDZD3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:500.
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PDZD3 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
0.1 ml/$460
PDZD3 Antibody - Immunohistochemistry of paraffin-embedded human kidney at dilution 1:100
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PDZD3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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PDZD3 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
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PDZD3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
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PDZD3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
PDZD3 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PDZD3 Rabbit anti-Human Polyclonal (aa119-435) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
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PDZD3 Rabbit anti-Human Polyclonal (aa258-285) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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PDZD3 Rabbit anti-Human Polyclonal (aa258-285) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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PDZD3 Rabbit anti-Human Polyclonal (aa258-285) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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PDZD3 Rabbit anti-Human Polyclonal (aa258-285) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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PDZD3 Rabbit anti-Human Polyclonal (aa258-285) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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PDZD3 Rabbit anti-Human Polyclonal (aa258-285) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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PDZD3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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PDZD3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
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PDZD3 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$649
PDZD3 Antibody - Western blot of Human HepG2. PDZD3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDZD3 Rabbit anti-Human Polyclonal (aa105-154) Antibody
Human
WB
Unconjugated
100 µl/$424
PDZD3 Antibody - Western blot of Human HepG2. PDZD3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDZD3 Rabbit anti-Human Polyclonal (aa105-154) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
PDZD3 Antibody - Western blot of Human HepG2. PDZD3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDZD3 Rabbit anti-Human Polyclonal (aa105-154) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
PDZD3 Antibody - Western blot of Human HepG2. PDZD3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDZD3 Rabbit anti-Human Polyclonal (aa105-154) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
PDZD3 Antibody - Western blot of Human HepG2. PDZD3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDZD3 Rabbit anti-Human Polyclonal (aa315-364) Antibody
Human
WB
Unconjugated
100 µl/$424
PDZD3 Antibody - Western blot of Human HepG2. PDZD3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDZD3 Rabbit anti-Human Polyclonal (aa315-364) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
PDZD3 Antibody - Western blot of Human HepG2. PDZD3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDZD3 Rabbit anti-Human Polyclonal (aa315-364) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PDZD3 Antibody - Western blot of Human HepG2. PDZD3 antibody dilution 1.0 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDZD3 Rabbit anti-Human Polyclonal (aa315-364) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
PDZD3 Antibody - PDZD3 Antibody western blot of ZR-75-1 cell line lysates (35 ug/lane). The PDZD3 antibody detected the PDZD3 protein (arrow).
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PDZD3 Rabbit anti-Human Polyclonal (aa258-285) Antibody
Human
WB
Unconjugated
400 µl/$393
PDZD3 Antibody - Western blot analysis of extracts of various cell lines, using PDZD3 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 30s.
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PDZD3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Viewing 1-25 of 30 product results



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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).