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Anti-PDZD3 Antibody (C-Terminus) IHC-plus™ LS-B268

Note: This antibody replaces LS-C2834

Ordering

Wt. Vol. Conc. Price
- 100 µl - Unavailable

Most Popular PDZD3 Antibodies

Anti-PDZD3 Antibody (C-Terminus) IHC-plus™ LS-B268
Rabbit Polyclonal to Mouse PDZD3
Mouse, Human, Rat
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image
Anti-PDZD3 Antibody (aa258-285) LS-C158567
Rabbit Polyclonal to Human PDZD3
Human
Western blot
Unconjugated
Western blot Image
Anti-PDZD3 Antibody (aa105-154) LS-C201888
Rabbit Polyclonal to Human PDZD3
Human
Western blot
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Mouse PDZD3
Mouse, Human, Rat
IHC - Paraffin, Western blot
Unconjugated

Details

Mouse PDZD3
Rabbit
Mouse, Human, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Antiserum
Unmodified

Applications

  • IHC - Paraffin (1:500)
  • Western blot

Specificity and Use

PDZD3 antibody was raised against a synthetic peptide made to the C-terminus of mouse PDZK2 / IKEPP
C-Terminus
PDZK2 / IKEPP.
Immunohistochemistry: LS-B268 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B268 was determined to be 1:500.

Packaging

Serum, 0.05% sodium azide.
Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
For research use only.

About PDZD3

NM_024791

PDZD3 Antibody, IKEPP Antibody, NHERF-4 Antibody, PDZ domain containing 2 Antibody, PDZK2 Antibody, NaPi-Cap2 Antibody, NHERF4 Antibody, PDZ domain containing 3 Antibody

Guanylyl cyclase C (GCC, or GUCY2C; MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR; MIM 602421), followed by a net efflux of ions and water into the intestinal lumen.

Immunohistochemistry

Immunohistochemistry
Anti-PDZD3 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B268 dilution 1:500.
 

Requested From: 
Date Requested: 3/27/2017

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