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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PDYN / ProDynorphin Antibody (aa1‑13) LS‑C22973
ProDynorphin antibody LS-C22973 is an unconjugated rabbit polyclonal antibody to ProDynorphin (PDYN) from rat, guinea pig, hamster and other species. Validated for IHC and RIA.
Antibody
Catalog
Size
Price
LS-C22973-100
100 µl
$710

Popular PDYN / ProDynorphin Products

Immunohistochemistry of paraffin-embedded human gastric cancer tissue.
Species: Human, Mouse, Rat
Applications: IHC, Western blot
PDYN / Preprodynorphin antibody LS-C135555 Western blot of 293T cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Rat
Applications: Western blot
PDYN / Preprodynorphin antibody LS-C116726 Western blot of HeLa lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Goat, Guinea pig, Hamster, Horse, Pig, Rabbit, Chicken, Zebrafish
Applications: Western blot
IHC of paraffin-embedded Colon ca using PDYN antibody at 1:250 dilution.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot
Western Blot analysis of PDYN expression in transfected 293T cell line by PDYN monoclonal antibody (M01), clone 2E12.Lane 1: PDYN transfected lysate(28.4 KDa).Lane 2: Non-transfected lysate.
Species: Human
Applications: Western blot, Immunoprecipitation, ELISA

Product Description

ProDynorphin antibody LS-C22973 is an unconjugated rabbit polyclonal antibody to ProDynorphin (PDYN) from rat, guinea pig, hamster and other species. Validated for IHC and RIA.
About PDYN / ProDynorphin
PDYN / ProDynorphin is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. P01213 NM_024411 NP_077722.1

PDYN Antibody, ADCA Antibody, Beta-neoendorphin-dynorphin Antibody, Leumorphin Antibody, Preprodynorphin Antibody, Spinocerebellar ataxia 23 Antibody, PENKB Antibody, Prodynorphin Antibody, Rimorphin Antibody, SCA23 Antibody, Leu-enkephalin Antibody, Preproenkephalin B Antibody, Proenkephalin-B Antibody


Specifications

Target
Pig PDYN / ProDynorphin
Host
Rabbit
Reactivity
Pig, Monkey, Rat, Guinea pig, Hamster (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Antiserum
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Radioimmunoassay (1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Dynorphin B 1-13: Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr (porcine) Prodynorphin 228-240.
Epitope
aa1-13
Specificity
The antibody blocks specifically with Dynorphin B 1-13. Cells are found in the paraventricular hypothalamic and the supraoptic nucleus in rat brain of colchicine treated 4% FA perfused tissue. Fibers are found in the lateral hypothalamus of both colchicine and normal rat brain of 4% FA perfused tissue. Species cross-reactivity: Porcine, rat, syrian hamster, guinea pig and rhesus monkey. Not tested on Human.
Usage
Suitable for use in Immunohistochemistry and RIA. Immunohistochemistry (frozen): 1:250-1:2500. Radioimmunoassay: 1:5000.
Presentation
PBS, 0.09% Sodium Azide, 1% BSA
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/18/2018

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