PDX1

pancreatic and duodenal homeobox 1

Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.

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Products

Antibodies (86)

Proteins (7)

ELISA Kits (6)

Type

Custom (2)

Over-Expression Lysate (2)

Primary (86)

Recombinant (5)

Sandwich (4)

Target

PDX1 (99)

Reactivity

Human (83)

Mouse (31)

Rat (26)

Bat (3)

Bovine (6)

Chimpanzee (6)

Dog (6)

Gibbon (6)

Hamster (6)

Horse (6)

Monkey (6)

Pig (3)

Rabbit (6)

Xenopus (3)

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Application

IHC (33)

IHC-Fr (2)

IHC-P (17)

WB (69)

Flo (3)

DB (14)

ELISA (38)

ICC (3)

IF (5)

IP (1)

Peptide-ELISA (3)

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Host

rabbit (67)

mouse (18)

goat (1)

Product Group

IHCPlus (2)

Isotype

IgG (42)

IgG1 (15)

IgG2a (2)

IgG2b,l (1)

Clonality

monoclonal mc (20)

polyclonal pc (66)

Clone

2G12 (1)

3F10 (1)

5A5 (2)

EP139 (2)

OTI1E1 (2)

OTI2A12 (2)

OTI3H3 (2)

OTI4D8 (2)

OTI4H7 (2)

OTI5D5 (2)

OTI7F7 (2)

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Format

96-Well Microplate (1)

96-Well Strip Plate (5)

APC (1)

APC Conjugated (6)

Azide-free (5)

Biotin Conjugated (8)

Carrier-free (7)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (8)

HRP Conjugated (8)

PE Conjugated (6)

Ready-to-Use (1)

Unconjugated (48)

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Epitope

pThr11 (14)

aa1-284 (9)

aa40-69 (7)

Thr11 (6)

aa429-459 (6)

N-Terminus (4)

aa36-85 (4)

40-120 aa (1)

aa100-200 (1)

aa136-169 (1)

aa186-215 (1)

aa21-55 (1)

aa27-76 (1)

p61 (1)

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Publications

No (99)

Sample Type

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (2)

Tag

6His, N-terminus (1)

GST (1)

His, N-Terminal (1)

His-GST (1)

Myc-DDK (Flag) (3)

Species

Human (5)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (2)

Select

Human PDX1 Protein (Recombinant 6His, N-terminus) (Tyr8-Arg277) - LS-G26476

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

33 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Mouse PDX1 (Sandwich ELISA) ELISA Kit - LS-F9697

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$854

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PDX1 Antibody (clone OTI3H3) LS-C340255

Antibody:

PDX1 Mouse anti-Human Monoclonal (OTI3H3) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

100 µl/$434

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PDX1 Antibody (clone OTI3H3, Carrier-free) LS-C791210

Antibody:

PDX1 Mouse anti-Human Monoclonal (Carrier-free) (OTI3H3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

PDX1 Antibody (aa36-85) LS-B11870

Antibody:

PDX1 Rabbit anti-Mouse Polyclonal (aa36-85) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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PDX1 Antibody (aa36-85, HRP) LS-C427194

Antibody:

PDX1 Rabbit anti-Mouse Polyclonal (aa36-85) (HRP) Antibody

Reactivity:

Xenopus, Bat, Rat, Hamster, Rabbit, Mouse, Dog, Bovine, Horse, Human, Monkey, Chimpanzee, Gibbon

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP

• Unconjugated
• HRP

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PDX1 Antibody (phospho-Thr11) LS-C97137

Antibody:

PDX1 Rabbit anti-Human Polyclonal (pThr11) Antibody

Reactivity:

Human

Applications:

DB

Format:

Unconjugated

Price:

400 µl/$393

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PDX1 Antibody (aa100-200) LS-C359335

Antibody:

PDX1 Rabbit anti-Human Polyclonal (aa100-200) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$386

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Human PDX1 Protein (Recombinant GST) (Full Length) - LS-G29075

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.08 kDa

Price:

2 µg/$439

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Human PDX1 (Sandwich ELISA) ELISA Kit - LS-F35579

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

PDX1 Antibody (clone OTI2A12) LS-C114333

Antibody:

PDX1 Mouse anti-Human Monoclonal (OTI2A12) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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PDX1 Antibody (clone OTI2A12, Carrier-free) LS-C784069

Antibody:

PDX1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2A12) Antibody

Reactivity:

Human

Applications:

IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

IHC-plus™ PDX1 Antibody (aa27-76) LS-B9244

(4.0) Rating

Antibody:

PDX1 Rabbit anti-Human Polyclonal (aa27-76) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

PDX1 Antibody (clone EP139) LS-C743595

Antibody:

PDX1 Rabbit anti-Human Monoclonal (EP139) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated

Price:

0.1 ml/$401; 0.5 ml/$594; 1 ml/$975

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PDX1 Antibody (clone EP139, Ready-to-Use) LS-C743476

Antibody:

PDX1 Rabbit anti-Human Monoclonal (Ready-to-Use) (EP139) Antibody

Reactivity:

Human

Applications:

IHC-Fr, IHC-P

Format:

Unconjugated, Ready-to-Use

Price:

3 ml/$401; 7 ml/$498; 15 ml/$737

• Unconjugated
• Unconjugated, Ready-to-Use

• Unconjugated
• Unconjugated, Ready-to-Use

Select

PDX1 Antibody (aa40-69) LS-C122297

Antibody:

PDX1 Rabbit anti-Human Polyclonal (aa40-69) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$734

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PDX1 Antibody (aa40-69, Biotin) LS-C280695

Antibody:

PDX1 Rabbit anti-Human Polyclonal (aa40-69) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PDX1 Antibody (aa40-69, FITC) LS-C280696

Antibody:

PDX1 Rabbit anti-Human Polyclonal (aa40-69) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PDX1 Antibody (aa40-69, APC) LS-C280694

Antibody:

PDX1 Rabbit anti-Human Polyclonal (aa40-69) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • APC

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Human PDX1 (Sandwich ELISA) ELISA Kit - LS-F20294

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Rat PDX1 (Sandwich ELISA) ELISA Kit - LS-F20295

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$783

Select

Mouse PDX1 Protein (Recombinant His-GST) (aa1-284) - LS-G25925

Source:

E. coli

Tag:

His-GST

Molecular Weight:

61.0 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$3,201

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PDX1 Antibody (clone 5A5) LS-C169167

Antibody:

PDX1 Mouse anti-Human Monoclonal (5A5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

PDX1 Antibody (clone 2G12) LS-C169186

Antibody:

PDX1 Mouse anti-Human Monoclonal (2G12) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

PDX1 Antibody LS-C405773

Antibody:

PDX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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