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PDK3

pyruvate dehydrogenase kinase, isozyme 3

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: pyruvate dehydrogenase kinase, isozyme 3
Family/Subfamily: Protein Kinase , PDK/BCKDK
Synonyms: PDK3, PDHK3
Target Sequences: NM_005391 NP_005382.1 Q15120

Publications (1)

1
VHL Dependent Expression of REDD1 and PDK3 Proteins in Clear-cell Renal Cell Carcinoma. Ilic BB, Antic JA, Bankovic JZ, Milicevic IT, Rodic GS, Ilic DS, Tulic CD, Todorovic VN, Damjanovic SS. Journal of medical biochemistry. 2018 January;37:31-38. [Full Text Article] [PubMed:30581339] [PMC:PMC6294108] Related Antibodies: LS-C111083.

☰ Filters
Antibodies (52)
Proteins (9)
Over-Expression Lysate (4)
Primary (52)
Recombinant (5)
PDK3 (61)
Human (33)
Mouse (29)
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Chimpanzee (6)
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ELISA (24)
rabbit (50)
mouse (2)
IgG (32)
IgG2a,k (1)
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monoclonal mc (2)
polyclonal pc (50)
2B11 (1)
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aa1-30 (7)
aa387-414 (7)
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aa74-123 (4)
aa102-351 (1)
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293T Cells (2)
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PDK3 Antibody - PDK3 antibody Western blot of OVCAR-3 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDK3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
PDK3 Antibody - Transfected 293T cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDK3 Rabbit anti-Human Polyclonal (aa74-123) Antibody
Human
WB
Unconjugated
100 µl/$424
PDK3 Antibody - Western blot of PDK3 Antibody in MCF-7 cell line lysates (35 ug/lane). PDK3 (arrow) was detected using the purified antibody.
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PDK3 Rabbit anti-Human Polyclonal Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
PDK3 Antibody - Immunohistochemistry of paraffin-embedded human heart tissue at dilution 1:100
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PDK3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) Antibody
Mouse
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (Biotin) Antibody
Mouse
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (FITC) Antibody
Mouse
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (APC) Antibody
Mouse
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (PE) Antibody
Mouse
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (Azide-free) (HRP) Antibody
Mouse
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PDK3 Antibody - Immunohistochemistry of paraffin-embedded mouse lung using PDK3 antibody at dilution of 1:100 (x40 lens).
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PDK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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PDK3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
PDK3 Antibody - Mouse Pdk3 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded mouse heart tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PDK3 Antibody
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PDK3 Rabbit anti-Human Polyclonal (aa102-351) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$332
PDK3 Antibody - PDK3 monoclonal antibody (M01), clone 2B11 Western Blot analysis of PDK3 expression in MCF-7.
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PDK3 Mouse anti-Human Monoclonal (2B11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
PDK3 Antibody
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PDK3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
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PDK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PDK3 Antibody - Positive Western Blot detected in Rat liver tissue. All lanes: Pdk3 antibody at 3 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 48 KDa. Observed band size: 48 KDa
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PDK3 Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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PDK3 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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PDK3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
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PDK3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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PDK3 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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PDK3 Rabbit anti-Human Polyclonal (Azide-free) Antibody
Human
ELISA, WB
Unconjugated, Azide-free
200 µl/$734
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PDK3 Rabbit anti-Human Polyclonal (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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PDK3 Rabbit anti-Human Polyclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Viewing 1-25 of 61 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).