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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PDGFRB / PDGFR Beta Antibody (phospho‑Tyr751) LS‑C9623
PDGFR Beta antibody LS-C9623 is an unconjugated mouse monoclonal antibody to PDGFR Beta (PDGFRB) from human and mouse. Validated for ELISA, IP and WB. Cited in 1 publication.
Antibody
Catalog
Size
Price
LS-C9623-100
100 µl
$575

Popular PDGFRB / PDGFR Beta Products

Anti-PDGFRB antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3667 concentration 20 ug/ml.
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, Western blot
Anti-PDGFRB antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5203 concentration 20 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin
Anti-PDGFRB antibody LS-A9413 IHC of human kidney, renal tubular epithelium in cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin
Anti-PDGFRB antibody LS-A9414 IHC of human kidney, glomerulus and renal tubular epithelium in cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human, Monkey, Bovine, Pig, Rabbit
Applications: IHC, IHC - Paraffin
Antibody
Species: Human, Baboon, Monkey
Applications: IHC, IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry

Product Description

PDGFR Beta antibody LS-C9623 is an unconjugated mouse monoclonal antibody to PDGFR Beta (PDGFRB) from human and mouse. Validated for ELISA, IP and WB. Cited in 1 publication.

Specifications

Target
Human PDGFRB / PDGFR Beta
Synonyms
PDGFRB, CD140B, Beta pdfgr, Beta type PDGFR, BPDGFR, CD140b antigen, IBGC4, JTK12, PDGF-beta R, PDGF-R-beta, PDGFR, PDGFRbeta, PDGF receptor beta, PDGF-R, PDGFbetaR, PDGFR Beta, PDGFR-1, PDGFR-beta, BetaPDGFR, Pdgf beta-receptor, PDGFR1, PDGFRB/CEV14 fusion gene
Host
Mouse
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2b Monoclonal
Conjugations
Unconjugated
Purification
Ascites
Modifications
Unmodified
Applications
  • Western blot (1:1000)
  • Immunoprecipitation (1:100)
  • ELISA
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding Tyr751 of human PDGF receptor beta (KLH coupled).
Epitope
pTyr751
Specificity
Detects endogenous levels of human PDGF receptor beta (190kD) only when phosphorylated at Tyr751. Does not cross-react with other tyrosine-phosphorylated proteins. Species cross-reactivity: mouse. Species sequence homology: rat.
Usage
Suitable for use in Western Blot, Immunoprecipitation and ELISA. Western Blot: 1:1000. Immunoprecipitation: 1:100.
Presentation
10 mM HEPES-Sodium, pH 7.5, 150 mM NaCl, 0.1 mg/ml BSA, 0.02% Sodium Azide, 50% Glycerol
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About PDGFRB / PDGFR Beta
Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. P09619 NM_002609 NP_002600.1


Publications (1)

1
Vascular pathology in dermatomyositis and anatomic relations to myopathology. Pestronk A, Schmidt RE, Choksi R. Muscle & nerve. 2010 42:53-61. (IHC; Human) [Full Text Article] [PubMed:20544925]

Customer Reviews (0)


Requested From: United States
Date Requested: 10/19/2018

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