Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
PDGFRB / PDGFR Beta antibody was raised against peptide (PAPRAEAEDSFL) corresponding to the amino acids 1095-1106 of human PDGF type B receptor Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Orangutan, Galago, Marmoset, Bovine, Dog, Horse, Pig (92%); Mouse, Rat (83%).
Recognizes PDGF type B receptor
30% glycerol, 0.07 M Tris-glycine, pH 7.4, 0.105 M sodium chloride, 0.035% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles. Store undiluted.
Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells.